3D and 2D organic hybrid perovskites, as well as double perovskites, have demonstrated their suitability for direct X-ray detection. However, the sensitivity and stability of 3D perovskite X-ray detectors are currently being hindered by the existing constraints on ion movement. Therefore, there is an immediate need to develop X-ray detectors that are both highly sensitive and stable while also being environmentally friendly.
View Article and Find Full Text PDFJ Infect Dev Ctries
November 2024
Introduction: Mycobacterium marinum is a well-known pathogenic non-tuberculous mycobacterium for skin and soft tissue infections. Infection, often presenting as superficial lesions, is seen after exposure of skin abrasions to contaminated water or infected fish and is known as "swimming pool" or "fish tank" granuloma. This study reported a case of M.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Designing high-performance electrocatalysts with superior catalytic activity and stability is essential for large-scale hydrogen production via water electrolysis. Heterostructure nanoarrays are promising candidates, though achieving both high activity and stability simultaneously, especially under high current densities, remains challenging. To this end, we have developed a cascade reaction process that constructs a series of heterostructure nanoarrays with rich heterointerfaces.
View Article and Find Full Text PDFPorcine reproductive and respiratory syndrome (PRRS), caused by the porcine reproductive and respiratory syndrome virus (PRRSV), is a severe and highly contagious disease that results in significant economic losses for the pig industry. Currently, vaccination is one of the most effective methods for controlling PRRS; however, due to the extensive genetic variation of PRRSV and the generation of homologous immunity, vaccines provide protective effects only against homologous strains and lack effective cross-protection against heterologous strains. Furthermore, PRRSV encodes a variety of proteins with immune escape functions, and the mechanisms underlying these functions are complex and not yet fully understood.
View Article and Find Full Text PDFPurpose: Adjacent disc degeneration (ADD) is a common postoperative complication after percutaneous kyphoplasty (PKP). However, risk factors for ADD after PKP have not been reported. This study aimed to determine whether osteoporotic vertebral compression fracture (OVCF) following PKP is associated with a high risk for ADD and to identify the risk factors for ADD.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
March 2025
A comprehensive understanding of the salinization of groundwater in the Guanzhong Basin, China, is crucial for ensuring sustainable groundwater development. However, the mechanism driving salinization in different regions of the basin remains unclear. Therefore, this study employed multivariate statistical methods, hydrochemical analysis, isotope studies, and hydrochemical modeling to uncover the factors and processes influencing groundwater salinization.
View Article and Find Full Text PDFCurr Cancer Drug Targets
October 2024
With the increasing development of productivity, new materials that allow for the efficient use of energy are slowly becoming a sought-after goal, as well as a challenge that is currently being faced. For this reason, we have made aerogels as the target of our research and prepared different series (CLPI (1-5)) of cross-linked polyimide aerogels by mixing and cross-linking the heat-insulating cross-linking agent 1,3,5-tris(4-aminobenzylamino)benzene (TAB) with polyamic acid solution. We created a three-dimensional spatial organization by using vacuum freeze-drying and programmed high-temperature drying, then controlled the concentration of the polyamidate solution to investigate the concentration and TAB's influence on aerogel-related properties.
View Article and Find Full Text PDFGlyoxal (GL) is a physiological reactive α-oxoaldehyde metabolite, produced by lipid peroxidation and autoxidation of glucose. In this work, a specific mitochondria-targeting fluorescent probe Z-GL for glyoxal has been developed by an introducing isopropyl group on the recognition site to tune the selectivity toward glyoxal. The probe showed high selectivity and sensitivity for glyoxal in an aqueous system.
View Article and Find Full Text PDFGiven the pollution prevalence of potentially hazardous elements (PTEs) in agricultural soils worldwide, it is crucial to establish a comprehensive approach to accurately assess soil contamination, and quantitatively allocate sources and source-specific risks. In the study, soil contamination was assessed through environmental capacity based on the local geochemical baseline established using PTE contents of the subsoil. The sources of PTEs were quantified through positive matrix factorization (PMF) and GIS mapping.
View Article and Find Full Text PDFBackground And Aims: Physicians are required to spend a significant amount of reading time of magnetically controlled capsule endoscopy. However, current deep learning models are limited to completing a single recognition task and cannot replicate the diagnostic process of a physician. This study aims to construct a multi-task model that can simultaneously recognize gastric anatomical sites and gastric lesions.
View Article and Find Full Text PDFWe develop a generic geometric formalism that incorporates both TT[over ¯]-like and root-TT[over ¯]-like deformations in arbitrary dimensions. This framework applies to a wide family of stress-energy tensor perturbations and encompasses various well-known field theories. Building upon the recently proposed correspondence between Ricci-based gravity and TT[over ¯]-like deformations, we further extend this duality to include root-TT[over ¯]-like perturbations.
View Article and Find Full Text PDFThe combination of chemotherapy and photodynamic therapy (PDT), enabled by core-shell nano-platforms, is a promising method to improve cancer therapy by overcoming hypoxia and boosting drug penetration in breast tumor. Core-shell magnetic (iron oxide: Fe3O4)@platinum-metal organic framework/epirubicin (abbreviated as M@Pt-MOF/EPI) nano-platform is considered an effective cancer therapeutic agent. Relatively small particle size, round shape, and specific response to pH, are the key features of these nanomaterials to be used as promising therapeutic agents.
View Article and Find Full Text PDFGlobal water resources affected by excessive nitrate (NO) have caused a series of human health and ecological problems. Therefore, identification of NO sources and transformations is of pivotal significance in the strategic governance of widespread NO contaminant. In this investigation, a combination of statistical analysis, chemical indicators, isotopes, and MixSIAR model approaches was adopted to reveal the hydrochemical factors affecting NO concentrations and quantify the contribution of each source to NO concentrations in surface water and groundwater.
View Article and Find Full Text PDFPurpose: This retrospective cohort study evaluated the efficacy and safety of percutaneous transforaminal endoscopic decompression (PTED) in elderly patients with degenerative lumbar scoliosis (DLS) associated with lumbar spinal stenosis (LSS).
Study Design: A matched comparison study.
Methods: In total, 97 patients with DLS associated with LSS who underwent PTED under local anesthesia between 2016 and 2021 were retrospectively analyzed.
Predicting protein-ligand binding sites is an integral part of structural biology and drug design. A comprehensive understanding of these binding sites is essential for advancing drug innovation, elucidating mechanisms of biological function, and exploring the nature of disease. However, accurately identifying protein-ligand binding sites remains a challenging task.
View Article and Find Full Text PDFDiabetic retinopathy (DR), a leading cause of blindness in diabetic patients, necessitates the precise segmentation of lesions for the effective grading of lesions. DR multi-lesion segmentation faces the main concerns as follows. On the one hand, retinal lesions vary in location, shape, and size.
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