Publications by authors named "Song Baoying"
Cerebral venous sinus thrombosis (CVST) is frequently observed in younger adults and features in large thrombus volume. Due to the triangular-like cross-sectional shape and large diameter of the superior sagittal sinus, all the commercially available artery stent retrievers are not suitable for venous vessels. In this study, a dumbbell-like stent was designed and fabricated by 3D braided technology using NiTi wires; it was manually rotatable and stretchable with controlled length/diameter ratios (2.
View Article and Find Full Text PDFThe neuroprotection of acute ischemic stroke (AIS) patients to alleviate the reperfusion injury is a long-standing problem. Although the intra-arterial selective cooling saline infusion (IA-SCSI) is a promising technique to improve the outcome of AIS, the clinical results are not sufficiently satisfactory. Magnesium-containing solutions such as magnesium sulfate (MgSO) can protect cells by modulating the intracellular Ca content in damaged cells, suggesting that they could be hypothermia infusion solution.
View Article and Find Full Text PDFBackground: Lack of a dedicated thrombectomy device for cerebral venous thrombosis hinders the recanalization ability of endovascular treatment (EVT). Novel NiTi-braided stent retriever (Venous-TD) is a dedicated venous sinus thrombectomy device. This study aims to demonstrate the safety and efficacy of Venous-TD.
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- The paper presents RGX, a comprehensive model developed to better predict outcomes for stroke patients, enabling more personalized treatment plans.
- It incorporates the SHAP model to clarify how various patient factors influence mortality predictions, addressing current gaps in understanding which clinical variables affect survival.
- The RGX model shows impressive accuracy rates of 92.18% with complete data and 84.62% with significant missing data, outperforming existing models and supporting the advancement of precision medicine.
Article Synopsis
- * A bibliometric analysis of research from 2009 to 2023 identified 106 relevant articles, revealing that China, the United States, and Japan lead in publications, while the Second Military Medical University is the most influential institution in this field.
- * Key findings show a growing trend in research, with frequent keywords like hydrogen, oxidative stress, inflammation, and apoptosis; future studies are expected to focus on hydrogen's role in early brain injury, ischemia-reperfusion injury, and hypothermia treatment.
Article Synopsis
- * While MT can have complications compared to anticoagulation alone, it shows better vessel recanalization rates and fewer complications in severe cases like large vessel occlusion strokes.
- * There is a need for more extensive research and clinical trials to assess the safety and effectiveness of MT for CVST, as well as advancements in endovascular treatment devices specifically for this condition.
Article Synopsis
- * A study tested a "biodegradable neuroprotective stent" made from magnesium, which releases magnesium and hydrogen locally to help protect the brain from injury during the recovery phase.
- * Results showed that magnesium improved neuron survival in lab tests and protected against various harmful effects in a rat model, suggesting that magnesium-based implants could be a promising treatment for brain ischemia.
Article Synopsis
- The study investigates the use of hypothermia as a treatment to reduce neural damage, compiling historical research and identifying future trends in this area from 2003 to 2023.
- It analyzed 2103 articles, revealing a steady increase in publications over the years, with the U.S. and the University of California System being the most prolific contributors.
- Key findings show a significant focus on hypothermia's effects on infants with hypoxic-ischemic encephalopathy and cardiac arrest, highlighting these areas as current research priorities.
Background: The neuroprotective effect of magnesium has been widely discussed, and its effectiveness has been confirmed by animal and clinical trials. However, there are still difficulties in clinical translation in diseases such as cerebral ischemia and subarachnoid hemorrhage. Therefore, it is necessary to analyze the literatures about neuroprotection of magnesium to reveal a more comprehensive knowledge framework, research hotspots and trends in the future.
View Article and Find Full Text PDFCerebral venous thrombosis (CVT) is a rare form of cerebrovascular disease that impairs people's wellbeing and quality of life. Inflammation is considered to play an important role in CVT initiation and progression. Several studies have reported the important role of leukocytes, proinflammatory cytokines, and adherence molecules in the CVT-related inflammatory process.
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