Hydrogen Peroxide Quantification Using Zero Dimensional Carbon Nanostructured Materials: A Review.

Hydrogen peroxide (HO) is suspected to promote cancer. Higher concentrations of HO have always harmed mammalian cells, other living things, as well as the environment. As well, elevated concentrations of HO might cause major health problems such as cancer, cardiovascular disease, asthma, Alzheimer's disease, etc.

Reactive Spindle Cell Nodule in the Pancreas Post Fine Needle Aspiration: A Case Report and Literature Review.

Reactive spindle cell nodules (RSCNs) that occur after fine needle aspiration (FNA) are commonly documented in the literature. They are benign proliferation of spindle cells with some mitotic figures and nuclear pleomorphism that arise after tissue injuries like FNA. These lesions are non-capsulated and surrounded by parenchyma of organ tissue.

Silicon dioxide incorporated cellulose acetate-mixed matrix membranes for Safranin-O removal from aqueous solutions.

Nanoparticle incorporated-mixed matrix membranes are renowned for their multifaceted advantages, including improved hydrophilicity, elevated solute rejection, enhanced mechanical robustness, and augmented chemical and thermal stability. The inherent hydrophilicity of silicon dioxide (SiO) nanoparticles, due to silanol groups (Si-OH), along with their high porosity and surface area, renders them an ideal reinforcing filler within polymer matrices, significantly strengthening structural integrity of membranes. In this work, SiO nanoparticles were incorporated in a cellulose acetate (CA) matrix to prepare CA/SiO adsorptive membranes using phase inversion method.

Design and assessment of tractor-driven chopping tilling and mixing machine for in-situ management of paddy straw.

In many Indian regions, paddy wheat is the main crop rotation and facing the problem of straw incorporation for seed bed preparation in short period. The handling of straw in combine harvested paddy fields is a significant issue in the paddy wheat rotation. In order to solve this issue, efforts were carried out to cut paddy straw into small pieces by the newly proposed counter-rotating blades, followed by the simultaneous incorporation of a rotary tiller into the soil.

MicroRNA-mediated regulation of neurotransmitter receptors in epilepsy: A systematic review.

Background: Pathogenesis of epilepsy involves dysregulation of the neurotransmitter system contributing to hyper-excitability of neuronal cells. MicroRNA (miRNAs) are small non-coding RNAs known to play a crucial role in post-transcriptional regulation of gene expression.

Methods: The present review was prepared following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, employing a comprehensive search strategy to identify and extract data from published research articles.

Effluent quality improvement in sequencing batch reactor-based wastewater treatment processes using advanced control strategies.

The treatment of wastewater is highly challenging due to large fluctuations in flowrates, pollutants, and variable influent water compositions. A sequencing batch reactor (SBR) and modified SBR cycle-step-feed process (SSBR) configuration are studied in this work to effectively treat municipal wastewater while simultaneously removing nitrogen and phosphorus. To control the amount of dissolved oxygen in an SBR, three axiomatic control strategies (proportional integral (PI), fractional proportional integral (FPI), and fuzzy logic controllers) are presented.

Cu-Amidobis(phosphine)-Catalyzed Direct Amidation of Unactivated Alkanes via C(sp)-H Activation.

Herein, we describe an acid-base-free, sustainable, and efficient method for direct amidation of unactivated alkanes and toluene derivatives, using the dimeric Cu complex [Cu{-PhPCHCONCHPPh-}] (here onward referred to as [PNP-Cu]). Using this method, C(sp)-N bond formation was achieved through the activation of very challenging C(sp)-H bonds in cycloalkanes, alkenes, allyl groups, and benzyl groups, with tolerance toward ketonic groups, heterocycles, and halide functionalities. One of the precatalysts, (PNHP-Cu-Npht) was isolated and structurally characterized.

Cu-amidobis(phosphine) catalyzed C(sp)-C(sp) direct homo- and hetero-coupling of unactivated alkanes C(sp)-H activation.

Herein, we present a Cu-dimer, [Cu{PhPCHC(O)NCHPPh-}], which catalyzed direct C(sp)-H homocoupling of benzyl and cycloalkane derivatives with excellent yields and regio-selectivity. The method is very simple and tolerates various functionalities. Synergistic metal-ligand cooperativity was observed in Cu-N bond cleavage and protonation of nitrogen, and facilitates a bifunctional pathway, minimising the free energy corrugation for catalytic intermediates.

Treatment with nanosomal paclitaxel lipid suspension conventional paclitaxel in metastatic breast cancer patients - a multicenter, randomized, comparative, phase II/III clinical study.

Background: A novel nanosomal paclitaxel lipid suspension (NPLS), free from Cremophor EL (CrEL) and ethanol, was developed to address the solvent-related toxicities associated with conventional paclitaxel formulation.

Objective: To evaluate the efficacy and safety of NPLS CrEL-based paclitaxel (conventional paclitaxel) in patients with metastatic breast cancer (MBC).

Design: A prospective, open-label, randomized, multiple-dose, parallel, phase II/III study.

Association between maternal stress and premature milk cortisol, milk IgA, and infant health: a cohort study.

Background: Maternal stress is pervasive in the neonatal intensive care unit (NICU). Maternal stress is associated with changes in human milk (HM) immunomodulatory agents, which may impact neonatal health. We sought to determine the association between maternal stress, HM immunoglobulin A (IgA) and cortisol, and to assess how these milk components correlate with infant immune and neurodevelopmental outcomes.

Mesenchymal stem cells-derived extracellular vesicles for therapeutics of renal tuberculosis.

Extrapulmonary tuberculosis with a renal involvement can be a manifestation of a disseminated infection that requires therapeutic intervention, particularly with a decrease in efficacy of conventional regimens. In the present study, we investigated the therapeutic potency of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) in the complex anti-tuberculosis treatment (ATT). A rabbit model of renal tuberculosis (rTB) was constructed by injecting of the standard strain Mycobacterium tuberculosis H37Rv into the cortical layer of the kidney parenchyma.

New Spinal Shortening Technique for Tethered Cord Syndrome: A Technical Note.

: To present a new spinal shortening technique for tethered cord syndrome. Tethered cord syndrome (TCS) is a debilitating condition leading to progressive neurological decline. Surgical detethering for TCS is the gold standard of treatment.

Assessment of Pathology Domain-Specific Knowledge of ChatGPT and Comparison to Human Performance.

Context.—: Artificial intelligence algorithms hold the potential to fundamentally change many aspects of society. Application of these tools, including the publicly available ChatGPT, has demonstrated impressive domain-specific knowledge in many areas, including medicine.

A review of microbial fuel cell and its diversification in the development of green energy technology.

The advancement of microbial fuel cell technology is rapidly growing, with extensive research and well-established methodologies for enhancing structural performance. This terminology attracts researchers to compare the MFC devices on a technological basis. The architectural and scientific successes of MFCs are only possible with the knowledge of engineering and technical fields.

Application of apophyllite and thomsonite natural zeolite as modified adsorbents for the removal of zinc from acid mine drainage.

Materials composed of natural zeolite have the potential to serve as highly effective adsorbents in the treatment of wastewater. The present study explores zeolite resin-based Apophyllite and Thomsonite as adsorbents for removing Zinc from acid mine drainage solution. The characteristics of the natural zeolites (Apophyllites and Thomsonite) are investigated using X-ray diffraction, Fourier-transform infrared spectroscopy and Field emission scanning electron microscopy analysis.

Smokeless Tobacco Use and Its Association with Type 2 Diabetes: A Case Control Study.

Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder characterized by hyperglycemia and insulin resistance. Its incidence is increasing globally, with a significant impact on public health. Smokeless tobacco (SLT) is a form of tobacco consumption that has been associated with various health risks, including potential effects on glucose homeostasis.

Clinical profile and microbiological spectrum of patients with continuous ambulatory peritoneal dialysis-associated peritonitis at a tertiary care center.

Background: We present risk factors, clinical profile, and microbiological spectrum of patients with continuous ambulatory peritoneal dialysis (CAPD)-associated peritonitis who were managed at our center.

Methods: All consecutive patients with CAPD-associated peritonitis who presented to our center between July 2018 and December 2019 were included in the study. Risk factors, microbiological spectrum, clinical profile, and outcome of patients were studied.

ZIF-8 decorated cellulose acetate mixed matrix membrane: An efficient approach for textile effluent treatment.

The textile industry is the second largest water-intensive industry and generates enormous wastewater. The dyes and heavy metals present in the textile effluent, even at their lower concentrations, can cause an adverse effect on the environment and human health. Recently, mixed matrix membranes have gained massive attention due to membrane property enhancement caused by incorporating nanofillers/additives in the polymer matrix.

Copper(I) Complexes of Amide Functionalized Bisphosphine: Proximity Enhanced Metal-Ligand Cooperativity and Its Catalytic Advantage in C()-H Bond Activation of Unactivated Cycloalkanes in Dehydrogenative Carboxylation Reactions.

The reactions of amide functionalized bisphosphine, -PhPCHC-(O)N(H)CHPPh- () (BalaHariPhos), with copper salts is described. Treatment of with CuX in a 1:1 molar ratio yielded chelate complexes of the type [CuX{(-PhPCHC(O)N(H)CHPPh-)}-κ] (X = Cl, ; Br, ; and I, ), which on subsequent treatment with KOBu resulted in a dimeric complex [Cu(-PhPCHC(O)(N)CHPPh-)] (). Interestingly, complexes - showed weak N-H···Cu interactions.

An Overview of Antihistamines and their Properties used for Treatment of Different Diseases.

Background: By comparing the histamine impact to the instant response to an injected foreign protein in previously sensitized animals, one might hypothesize that histamine may be involved in this reaction. Through all four of the recognized types of histamine receptors, histamine is also essential for the control of immunological function and acute and chronic allergic inflammation.

Methods: Recent evidence points to anti-IgE antibodies and specific antibodies to cytokines like IL-4 or IL-5 that are associated with allergic inflammation as probable causes of Allergic Rhinitis.

Whole-genome sequencing and phylogenetic analysis of coxsackievirus-A16 strains causing hand, foot and mouth disease (HFMD) in India.

Hand, foot and mouth disease (HFMD) is a common childhood infectious disease, caused by enteroviruses (EVs), which can present with typical or atypical lesions. The illness is self-limiting, but it can also have serious complications. Since 1997, HFMD infections have become endemic and have increased to epidemic proportions across the Asia Pacific region, including India.

Unveiling Various Facades of Stem in Food: Medicinal and Nutraceutical Aspects.

Natural products with curative properties are gaining immense popularity in scientific and food research, possessing no side effects in contrast to other drugs. Guduchi, or , belongs to the menispermaceae family of universal drugs used to treat various diseases in traditional Indian literature. It has received attention in recent decades because of its utilization in folklore medicine for treating several disorders.