Rongalite as a C1 Source: Sulfonylmethylation of Indoles with Aryl/Alkyl Hydrazides and Sulfinates.

Herein, we present a sulfonylmethylation of indoles with aryl/alkyl hydrazides and sulfinates that provides viable access to sulfone compounds using rongalite as a C1 source. This protocol features readily available chemicals and simple operations, and the products were obtained in moderate to good yields.

Rongalite as a Sulfone Source: Sulfonylation of para-Quinone Methides and Alkyl/allyl Halides.

A one-pot three-component reaction using p-quinone methides, rongalite and alkyl/allyl halides has been described. The corresponding unsymmetrical sulfones were obtained in good yields under mild reaction conditions in the absence of any metal, base or any other additive.

1,6-Conjugate-Addition-Induced [2 + 1] Annulation of -Quinone Methides and Pyrazolones: Synthesis of Bis-Spiro Compounds with Contiguous Quaternary Spiro-Centers.

A diastereoselective formal 1,6-conjugate-addition-mediated [2 + 1] annulation reaction using -quinone methides and pyrazolones has been described. The corresponding bis-spiro[cyclohexadienone-cyclopropane-pyrazolone] compounds were obtained in very good yield under mild reaction conditions.