Incidence of and risk factors for cardiovascular complications after thoracic surgery for noncancerous lesions.

Objective: The purpose of this study was to determine the incidence of and risk factors for cardiovascular complications after thoracic surgery for noncancerous lesions.

Design: Retrospective cohort study.

Setting: A tertiary medical center.

Association of positive fluid balance and cardiovascular complications after thoracotomy for noncancer lesions.

Objective: The purpose of this study was to explore the influence of positive fluid balance on cardiovascular complications after thoracotomy for noncancer lesions.

Methods: After approval from an institutional review board, a retrospective cohort study was conducted. All consecutive patients undergoing thoracotomy between January 1, 2005 and December 31, 2011 in a single medical center were recruited.

The use of continuous thoracic paravertebral nerve block under direct vision for postoperative pain management in thoracic surgery.

Objective: The purpose of the present study was to determine the quality of analgesia of continuous thoracic paravertebral nerve block after thoracic surgery by inserting a catheter under direct vision and assessing complications related to the analgesia technique.

Material And Method: Thirty patients with ASA I-III scheduled for pulmonary resection were enrolled in the present prospective study. Posterolateral thoracotomy was done by one surgeon.

Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women.

Lung cancer is a major cause of cancer-related death in developed countries, and its incidence in developing countries is increasing. In Thailand, cancer incidences differ greatly from region to region, and lung cancer is the most common cancer in the northern Thai population. The polymorphic frequency of 10 genetic susceptibility genes and their association with lung cancer were examined in a northern Thai population: CYP1A1 (MspI), CYP1A1 (Ile462Val), CYP2E1 (PstI), CYP2E1 (DraI), GSTM1, GSTT1, MPO (AciI), OGG1 (Ser326Cys), TP53 (Arg72Pro), and MMP1(AluI).

Simplified approaches for the development of an ELISA to detect circulating autoantibodies to p53 in cancer patients.

Background: The recognition that human tumors stimulate the production of autoantibodies has initiated the use of this immune response as serological markers for the early diagnosis and management of cancer. The enzyme-linked immunosorbent assay (ELISA) is the most common method used in detecting autoantibodies, which involves coating the microtiter plate with the tumor associated antigen (TAA) of interest and allowing serum antibodies to bind. The patient's sample is directly in contact with the coating antigen so the protein used for coating must be pure to avoid non-specific binding.