Genetic variants and risk of thyroid cancer among Iranian patients.

The definition of an exclusive panel of genetic markers is of high importance to initially detect among this review population. Therefore, we gave a summary of each main genetic marker among Iranian patients with thyroid cancer for the first time which were classified based on their cellular function. Due to the results, a significant relationship was found between SNP in codons 194, 280, and 399 (C1), Allele 3434Thr (C7), GC or CC genotype 31, G/C (Survivin), 399G>A (C1), 9I (vitamin D receptor), G-D haplotype (2), TT genotype, -656 G/T (18), TAGTT haplotype (18), G allele in +49 A>G (A-4), +7146 G/A (1.

Genetic polymorphisms associated with polycystic ovary syndrome among Iranian women.

Polycystic ovary syndrome (PCOS) involves abnormalities in ovarian, reproductive, and metabolic systems. Genetic polymorphisms associated with individual differences and variations might be related to complex disorders with unknown causes, including PCOS. Several leading genetic markers with known cellular functions have been identified among Iranian women presenting with PCOS.

Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review.

Colorectal cancer has been considered as one of the complicated multi-stage processes after adenoma-carcinoma sequence. Therefore, studies of the molecular dysregulation basis could present information on the recognition of the potent biomarkers and treatment targets for this disease. Even though outcomes of the patients with colorectal cancer have been improved largely with current annual screening plans, it is necessary to have reliable prognostic biomarkers because of the disease heterogeneity.