Publications by authors named "Somayeh Maghsoodloorad"
Molecular analysis of antifolate resistance-associated genes-dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) of Plasmodium vivax is important in predicting the emergence of drug resistance to sulphadoxine-pyrimethamine (SP). The present study aimed to determine the polymorphism of dhfr and dhps genes in P. vivax field isolates.
View Article and Find Full Text PDFas free-living parasites are scattered ubiquitously, throughout the world. This study was aimed to evaluate the presence of spp. genotypes in the recreational water sources in Gorgan County, the capital of Golestan Province using both morphological and molecular approaches.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the dihydropteroate synthetase gene (dhps) polymorphism in Plasmodium vivax in Hormozgan Province, Iran, focusing on mutations linked to sulfadoxine resistance.
- A total of 118 P. vivax isolates were analyzed from blood samples collected between 2007-2008 using PCR and sequencing methods.
- Although mutations were found at a new codon (421), the main target codons for resistance remained unchanged, suggesting that P. vivax in this region is still susceptible to sulfadoxine treatment.