Publications by authors named "Somayeh Ansarimoghaddam"
Background: Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator. It plays a vital role in immune response against the oral disease. MIF is a regulator of innate immunity, and bacterial antigens can stimulate serum level of this protein.
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- The study examined the link between IL-6 (-174G/C) gene polymorphisms and tissue changes in patients with chronic periodontitis (CP).
- It involved analyzing gingival samples from 60 individuals, comparing those with CP to healthy controls, and assessing the volume density of various gingival components through specific techniques.
- The results indicated no significant relationship between IL-6 gene variations and the structural parameters of interdental papilla in CP patients.
Background. Interferon gamma (IFN-γ) is an immune regulatory cytokine that acts through its receptor and plays important role in progression of inflammatory disease such as chronic periodontitis (CP). The purpose of this study was to determine the differences in the distribution of IFN-γ (+874A/T) and IFN-γR1 (-611A/G, +189T/G, and +95C/T) gene polymorphisms among CP and healthy individuals and to investigate relationships between these polymorphisms and susceptibility to CP.
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