Osteoblastic cell response to AlO-Ti composites as bone implant materials.

Alumina-titanium (AlO-Ti) composites with enhanced mechanical and corrosion properties have been recently developed for potential applications in orthopaedics and hard tissue replacements. However, before any clinical use, their interactions with biological environment must be examined. The aim of this study, therefore, was to assess the biocompatibility of three AlO-Ti composites having 25, 50, and 75 volume percentages of titanium.

Corrosion of AlO-Ti composites under inflammatory condition in simulated physiological solution.

Alumina-titanium composites have shown good mechanical properties which makes them promising for orthopedic applications. The placement of an orthopedic implant involves an invasive procedure which stimulates a localized inflammatory response causing an acidic environment around the implant. This makes the study on corrosion more critical.