Incorporation of Functionalized Halloysite Nanotubes (HNTs) into Thin-Film Nanocomposite (TFN) Nanofiltration Membranes for Water Softening.

Incorporating nanoparticles (NPs) into the selective layer of thin-film composite (TFC) membranes is a common approach to improve the performance of the resulting thin-film nanocomposite (TFN) membranes. The main challenge in this approach is the leaching out of NPs during membrane operation. Halloysite nanotubes (HNTs) modified with the first generation of poly(amidoamine) (PAMAM) dendrimers (G1) have shown excellent stability in the PA layer of TFN reverse-osmosis (RO) membranes.

Capsaicin-loaded alginate nanoparticles embedded polycaprolactone-chitosan nanofibers as a controlled drug delivery nanoplatform for anticancer activity.

Nanocarrier-based drug delivery systems have been designed into various structures that can effectively prevent cancer progression and improve the therapeutic cancer index. However, most of these delivery systems are designed to be simple nanostructures with several limitations, including low stability and burst drug release features. A nano-in-nano delivery technique is explored to address the aforementioned concerns.

Surface Heparinization of a Magnesium-Based Alloy: A Comparison Study of Aminopropyltriethoxysilane (APTES) and Polyamidoamine (PAMAM) Dendrimers.

Magnesium (Mg)-based alloys are biodegradable metallic biomaterials that show promise in minimizing the risks of permanent metallic implants. However, their clinical applications are restricted due to their rapid in vivo degradation and low surface hemocompatibilities. Surface modifications are critically important for controlling the corrosion rates of Mg-based alloys and improving their hemocompatibilities.

A hydrogel-fiber-hydrogel composite scaffold based on silk fibroin with the dual-delivery of oxygen and quercetin.

Supplying sufficient oxygen within the scaffolds is one of the essential hindrances in tissue engineering that can be resolved by oxygen-generating biomaterials (OGBs). Two main issues related to OGBs are controlling oxygenation and reactive oxygen species (ROS). To address these concerns, we developed a composite scaffold entailing three layers (hydrogel-electrospun fibers-hydrogel) with antioxidant and antibacterial properties.

Hybrid electrospun scaffolds based on polylactic acid/ PAMAM dendrimer/gemini surfactant for enhancement of synergistic antibacterial ability for biomedical application.

Hybrid electrospun scaffolds based on poly (L-lactic acid) (PLLA)/poly (amidoamine) (PAMAM-G) dendrimer/gemini surfactant were fabricated for the enhancement of synergistic antibacterial activities. The second generation of poly (amidoamine) (PAMAM-G) and cationic gemini surfactant were utilized to functionalize the optimum electrospun scaffolds. The gelatination process was utilized to improve the wettability of PLLA scaffolds to extend cell attachment and cell proliferation.

Synthesis and characterization of tetraethylene pentamine functionalized MIL-101(Cr) for removal of metals from water.

Purpose: Metal contamination in water is a worldwide persistent problem. We developed a nano-adsorbent, TEPA-MIL-101(Cr) that exhibits effective removal of heavy metals from real water samples.

Methods: MIL-101(Cr) was synthesized under solvo-thermal condition.

Cationic gemini surfactant properties, its potential as a promising bioapplication candidate, and strategies for improving its biocompatibility: A review.

Gemini surfactants consist of two cationic monomers of a surfactant linked together with a spacer. The specific structure of a cationic gemini surfactant is the reason for both its high surface activity and its ability to decrease the surface tension of water. The high surface activity and unique structure of gemini surfactants result in outstanding properties, including antibacterial and antifungal activity, anticorrosion properties, unique aggregation behaviour, the ability to form various structures reversibly in response to environmental conditions, and interactions with biomacromolecules such as DNA and proteins.

Ionic conductive nanocomposite based on poly(-lactic acid)/poly(amidoamine) dendrimerelectrospun nanofibrous for biomedical application.

The modification of poly (-lactic acid) (PLLA) electrospun nanofibrous scaffolds was carried out by blending with second-generation poly amidoamine (PAMAM) for enhancement of their ionic conductivity. The samples containing PLLA and various amounts of PAMAM (1%, 3%, 5%, and 7% by wt.) were fabricated by electrospinning techniques.

Hemostatic Electrospun Nanocomposite Containing Poly(lactic acid)/Halloysite Nanotube Functionalized by Poly(amidoamine) Dendrimer for Wound Healing Application: In Vitro and In Vivo Assays.

The main challenge in treating injuries is excessive bleeding whereas intervention is required if the body's hemostatic systems fail to control the bleeding. Herein, a novel nanocomposite consisting of poly(lactic acid) (PLA) and poly(amidoamine) (PAMAM) dendrimer functionalized halloysite nanotube (HNT) with a highly porous structure via electrospinning is developed. HNT is functionalized by PAMAM via divergent synthetic routes from zero to third-generation numbers.

Treatment with edaravone improves the structure and functional changes in the hippocampus after chronic cerebral hypoperfusion in rat.

This study aimed to find out cellular and electrophysiological effects of the edaravone (EDR) administration following induction of vascular dementia (VaD) via bilateral-carotid vessel occlusion (2VO). The rats were randomly divided into control, sham, 2VO + V (vehicle), and 2VO + EDR groups. EDR was administered once a day from day 0-28 after surgery.

Amine-terminated dendritic polymers as promising nanoplatform for diagnostic and therapeutic agents' modification: A review.

It is often challenging to design diagnostic and therapeutic agents that fulfill all functional requirements. So, bulk and surface modifications as a common approach for biomedical applications have been suggested. There have been considerable research interests in using nanomaterials to the prementioned methods.

The odour assessment of thyme essential oils in electrospun fibre mat with a virtual sensor array data and its relation to antibacterial activity.

The ability of a single-sensor gas diagnosis device (SSGDD) as a virtual sensor array data to appraise thyme essential oils (TEO) based on its quantitatively release rate from nanofibres was aimed. To form nylon 6 fragrant electrospun nanofibre, TEO was added as a natural antibacterial substance under homogeniser to make a stable emulsion. The optimised nanofibre inactivated against Escherichia Coli and Staphylococcus Aureus bacteria up to >75% at once and to > 41.

Fabrication of electrospun ibuprofen-loaded poly(vinyl alcohol)/hyper-branched poly(ethylenimine) fibers and their release behaviors.

A novel transdermal drug delivery system for the release of ibuprofen (IBU) was fabricated poly(vinyl alcohol)/hyper-branched poly(ethylene imine) (PVA/PEI) nanofibrous membranes. Hence, PVA/PEI solutions were electrospun at different PVA/PEI mass ratios of 100/0, 85/15, 75/25, and 65/35. SEM observations illustrated that the diameters of collected fibers to be 125-161 nm.

Amine-terminated dendritic polymers as a multifunctional chelating agent for heavy metal ion removals.

In this study, amine-terminated hyperbranched PAMAM (polyamidoamine) polymer (AT-HBP) was synthesized as a multifunctional chelating agent to remove two heavy metal ions (Cr(III) and Cu(II)) from the simulated wastewater solutions. The AT-HBP was characterized by Fourier transformed infrared (FTIR), dynamic light scattering (DLS), and proton nuclear magnetic resonance (H NMR) analysis. The removal process was carried out in two different methods, centrifuged process and ultrafiltration.

Electrospun nanofibers comprising of silk fibroin/gelatin for drug delivery applications: Thyme essential oil and doxycycline monohydrate release study.

In this study, a nanofibrous electrospun substrate based on the silk fibroin (SF) and gelatin (GT) polymers were prepared and evaluated. The SF/GT blended solutions were prepared with various ratios of GT in formic acid and electrospun to obtain bead-free fibers. Results showed that addition of GT to SF increased nanofiber's diameter, bulk hydrophilicity, surface wettability, mass loss percentage, but decreased Young's modulus, tensile strength, and porosity of the SF/GT mats.

QSAR Modeling of COX -2 Inhibitory Activity of Some Dihydropyridine and Hydroquinoline Derivatives Using Multiple Linear Regression (MLR) Method.

COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure-activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R) of 0.972 and 0.

Preparation and catalytic activity of bone-char ash decorated with MgO - FeNO for ozonation of reactive black 5 dye from aqueous solution: Taguchi optimization data.

Reactive dye is one of the most applicable dyes in textile industries which its release to the water bodies creates a concern for environmentalists. Here, in this data article a bone-char (BC) ash decorated with MgO-FeNO for removing reactive black 5 (RB5) dye in a catalytic ozonation process (COP) system. Operational parameters data such as initial RB5 concentration, pH, catalyst dosage, and reaction time were optimized using Taguchi method.