Publications by authors named "Somasekharan Nair Rajam Suja"
L. is a woody climber or liana distributed in south East Asia. It is a traditional medicinal plant with excellent curative effects against diarrhea, dysentery, and other stomach disorders.
View Article and Find Full Text PDFArticle Synopsis
- Spices, particularly a blend called Trikatu (ginger, black pepper, long pepper), may help manage viral infections and improve the immune system, but scientific evidence is needed to support their use as nutraceuticals.
- A Trikatu syrup was developed and tested on Wistar Albino rats, showing that it enhanced cell-mediated immunity as observed by increased footpad thickness.
- The study emphasizes the need for further validation to confirm the immunomodulatory effects of the syrup and its potential health benefits, especially in light of the COVID-19 pandemic.
Sub-chronic oral toxicity assessment (90 days) of ethanolic fraction of leaves of (R. Br. ex Benn.) Rob. in rodents: A lesser known ethnomedicinal plant from the Cholanaickan tribal community, India.
Interdiscip Toxicol
October 2018
The objective of the present study was to evaluate the safety of long term consumption of ethanolic fraction of leaves (NCEF) in rodents. The NCEF was subjected to detect the presence of various phytoconstituents. In acute oral toxicity study, graded doses of NCEF was administered in mice and were observed up to 14 days.
View Article and Find Full Text PDFAmeliorative effect of alkaloid extract of Cyclea peltata (Poir.) Hook. f. & Thoms. roots (ACP) on APAP/CCl4 induced liver toxicity in Wistar rats and in vitro free radical scavenging property.
Asian Pac J Trop Biomed
February 2014
Objective: To evaluate the hepatoprotective and antioxidant properties of alkaloid extract of Cyclea peltata (C. peltata) against paracetamol/carbon tetra chloride induced liver damage in Wistar rats.
Methods: In vivo paracetamol/carbon tetrachloride induced liver damage in Wistar rats, in vitro free radical scavenging studies, HPTLC estimation of tetrandrine and direct analysis in real time- mass spectrometry of alkaloid extract of C.