[Clinical and functional results of bifocal IOLs implanted during combined cataract and glaucoma surgery].

Unlabelled: At present, implantation of multifocal IOLs in patients with primary open-angle glaucoma (POAG) remains questionable.

Purpose: To comparatively analyze the clinical and functional effectiveness of bifocal IOLs implanted during combined cataract and glaucoma surgery.

Material And Methods: The prospective study included 41 patients (75 eyes) with presbyopia and POAG who underwent one-stage cataract phacoemulsification with implantation of a multifocal IOL and non-penetrating deep sclerectomy (NPDS) with lens capsule.

[Gastric erosions: pathogenesis, clinical features, diagnosis, and treatment].

Recent data on etiology, pathogenesis, diagnosis, and treatment of gastric erosion are reviewed. Classification of acute and chronic erosions is proposed. The authors point out to the lack of documented scientific information related to the role and significance of erosions in gastroduodenal pathology.

Effect of drugs with various mechanisms of action on propulsive activity of the small intestine.

We studied the effect of drugs with various mechanisms of action on propulsive activity of the small intestine in healthy rats. Blockade of the major inhibitory influences realized via nonadrenergic noncholinergic inhibitory effector neurons was not followed by stimulation of intestinal transit. Propulsive activity of the small intestine increased upon treatment with drugs, whose effects are realized via acetylcholine or acetylcholine and serotonin.

Effect of NO synthesis blocker on electrical activity of rat stomach and small intestine in the early postoperation period.

The effect of NO on electrical activity of the stomach and small intestine was studied in chronic experiments on rats during the early postoperation period. Generation of migrating myoelectric complex in the stomach and small intestine was impaired after abdominal surgery. Administration of NO synthesis blocker suppressed the inhibitory influences, which potentiated generation of the myoelectric complex in the small intestine.

[Assessment of effectiveness of livolin forte in the treatment of patient with steatohepatitis].

The article analyzes efficacy of the drug livolin in the treatment of patients with fatty hepatosis. It is shown that livolin promotes a rapid arresting of clinical symptomatology, normalization of biochemical indices, makes for improvement of physical-and-chemical properties of the bile.

[Effect of enterally administrated oxygenated water on electrical activity of the small intestine in early postoperative period in rats].

The effect of oxygen, structurally-binded with water (oxygen water), on electrical activity of rat jejunum in early postoperative period. It was shown, that in contrast to effect of 0.9% NaCl, there is normalization of electrical activity parameters (frequency and slow wave amplitude) of jejunum in early postoperative period under the influence of oxygen water.

[Use of enterol in the treatment of diseases complicated by diarrhea syndrome].

The article analyses data on clinical efficacy of the drug enterol in patients with chronic pancreatitis and chronic atropic gastritis. The use of enterol in a complex therapy has been shown to favour quick dispelling of the pain and dyspeptic syndromes, normalization of stools, elimination of intestinal dysbacteriosis or alleviation of its gravity.

Effect of mesodiencephalic modulation on small intestinal mucosa after massive blood loss in rats.

Effect of mesodiencephalic modulation on small intestinal mucosa was studied in rats subjected to massive blood loss. Massive blood loss induced structural changes in intestinal epitheliocytes typical of tissue hypoxia: intraintestinal edema, mitochondrial alterations, and microcirculation disturbances. A single session of mesodiencephalic stimulation carried out 60 min after massive blood loss produced a pronounced adaptive effect, restored disturbed structure of the intestinal villi, and induced compensatory hypertrophy of the mitochondria.

[Utilization of glucose, valine, glycerin and palmitic acid by energy and anabolic pathways of metabolism in rats].

Possibility of evaluation of nutrients use by energy and anabolic ways by measurement in blood of radioactivity of water formed from labelled by tritium precursors was studied. The experiment was made on rats, which consecutively with interval 1.5-2 weeks were given intravenous indicative amount of 3H2(2,3)-valine, 1-14C-glucose, 6-3H-glucose, 3H2(1,3)-glycerin and 3H2(9,10)-palmitic acid.

[A trial of the use of Maldroxal in treating patients with duodenal peptic ulcer].

The foreign-made drug preparation maldroxal the formulation of which includes aluminium hydroxide, magnesia hydroxide and dimeticon, is an effective medicine making for the instant relief of pain and dyspeptic syndromes; it is capable of exerting an antiinflammatory effect. It has also been ascertained that maldroxal fails to influence much the elimination of H. p.

[The effect of shigellae on delayed hypersensitivity in mice infected by different routes].

The influence of virulent and avirulent shigellae on delayed hypersensitivity in the case of infection by different methods has been examined. It was found that the stimulating effect of avirulent shigellae and suppressive effect of virulent shigellae were displayed after intranasal infection. Intraperitoneal and intravenous infection was accompanied by only immunosuppressive influence, which was displayed by the virulent bacteria.

Peculiarities of the distribution of man-made radionuclides in several European seas.

Results of a study on the distribution of the man-made radionuclides 137Cs and 90Sr in the surface waters of several European seas are presented. Based on an analysis of the ratio of these two radionuclides, an attempt was made to isolate the 'Chernobyl water' and to estimate the contribution of 'Chernobyl radioactivity' to the total radioactivity in the waters of the seas investigated.

[Interaction of rabbit skeletal muscle glycogen synthase I with substrate analogs--oxo-UDP hydrazones].

Inhibition of rabbit skeletal muscle glycogen synthase I was studied by using several synthetic substrate analogs: dansylhydrazone of oxo-UDP, 3-hydroxy-2-naphthoylhydrazone of oxo-UDP, salicyloylhydrazone of oxo-UDP, 1-oxyl-2,2,5,5-tetramethylpyrrolidine-3-carbonylhydrazone of oxo-UDP, N'-(dansyl)hydrazinocarbonylhydrazone of oxo-UDP and N'-(fluorenylidene-9)-hydrazinocarbonylhydrazone of oxo-UDP. All these compounds (with the exception of the nitroxyl-containing hydrazone) were characterized by a nonlinear dependence of the reverse reaction rate on the analog concentration in Dixon coordinates. The parabolic type of inhibition was due to the fact that the analogs tested except for the nitroxyl-containing hydrazone were able to interact both with the active center of the enzyme and with the FMN-binding site.

[Acoustic impedance measurement in the diagnosis of hypoacusis in children].

In 1986-1988, we examined 1105 children no older than 15 years with various forms of hypoacusis. It was found that measurement of acoustic impedance can help topical diagnosis at any age, especially in children younger than 3 years. In 1988, we examined 350 children with conductive hypoacusis.

[Interaction of glycogen synthase from rabbit skeletal muscles with 1,5-gluconolactone].

1.5-Gluconolactone was shown to inhibit in a competitive manner the activity of both I- and D-forms of rabbit skeletal muscle glycogen synthase. Unlike other known inhibitors (UDP and adenyl nucleotides) the affinity of the enzyme D-form for 1.

[Inhibition of glycogen synthase I from rabbit skeletal muscles by 1,5-gluconolactone].

The effect of 1.5-gluconolactone on the activity of rabbit skeletal muscle glycogen synthase I was investigated. Using statistic methods (pair regressive analysis) and computer analysis on a Robotron EC 1834 personal computer, it was found that 1.

[Turbidimetric method of determination of glycogen synthase activity in rabbit skeletal muscles].

A turbidimetric procedure is described, which involves the monitoring of changes in glycogen turbidity at wavelengths above 300 nm and continuous recording of rabbit skeletal muscle synthase activity. The recalculation coefficients were found to be equal to 1.69 +/- 0.

[Substrate specificity of glycogen synthase from rabbit skeletal muscles].

Nitrous bases were shown to play an essential role in the specificity of active and adenyl nucleotide binding sites. Pyrimidine base determines the substrate specificity of rabbit skeletal muscle glycogen synthase; a crucial role in this process is ascribed to the lactam fragment of the pyrimidine cycle. The 2-oxo group was also shown to be involved in substrate binding.

[Laser exposure of the blood as a method of preventing inflammatory complications following cesarean section].

Blood laser action (red spectrum, a wavelength of 628 nm, pulsed periodic quasi-continuous duty), a noninvasive tool, was demonstrated to stimulate the immune forces of the body, which showed a 2-fold or more decrease in the incidence of inflammatory complications after cesarean operation.

[Interaction of glycogen synthase of rabbit skeletal muscles with flavin mononucleotide].

The effect of flavin mononucleotide (FMN) on the activity of the I- and D-forms of rabbit skeletal muscle glycogen synthase has been studied for the first time. FMN has been shown to inhibit in a noncompetitive fashion the both forms of the enzyme, the D-form being more sensitive to the effect of the inhibitor. It has been shown also that glycogen synthase has three different sites involved in the interaction with inhibitors, namely, and active site, an adenyl nucleotide binding site and a FMN binding site.

[Electroacoustic correction of hearing in children].

Electroacoustic correction of hearing impairment is of crucial importance for children because it improves their rehabilitation and mental development. The principal objective of hearing corrective measures is to provide patients with hearing aids selected as early as possible on an individual basis. When selecting hearing aids, many clinical and audiological factors should be taken into consideration.

[Late thrombo-embolic complications after heart valve prosthesis].

A follow-up study of 444 patients with artificial heart valves of different makes demonstrated increased wear and thrombogenic properties of the hemispheric MKC-27 prosthesis, used in mitral position, over 5 years of follow-up. High risk of thrombo-embolic complications is related to interrupted anticoagulant treatment. Their rate could be reduced through improving the quality of anticoagulant treatment, i.

[Response of the rat pancreas to the effects of secretin and pancreozymin under conditions of different nutrition].

A study conducted on intact and castrated male rats with cannulated biliary-pancreatic ducts has shown that long-term protein deficiency in the ration leads to decreased secretion of pancreatic juice, lowers activity of amylase, alkaline ribonuclease, trypsin, lipase in the juice, and changes pancreatic response to the action of secretin, pancreozymin or their mixture, that is especially pronounced in the castrated rats.