[Correlation of TMJ structures and craniocervical area position in partial dental loss].

The purpose of the study was to determine the correlation features in position of the TMJ and the atlantoaxial compound in presence of dentition defects. The study included 20 patients (10 males and 10 females) aged 37 to 59 years with mandible terminal dentition defects. The comparison group included 20 patients of men and women equally, aged from 18 to 29 years with intact dentition.

[Long-term follow-up of patients with refractory systemic lupus erythematosus during rituximab treatment].

Aim: To evaluate the impact of anti-B-cell therapy on the clinical and immunological parameters of systemic lupus erythematosus (SLE) activity, on the time course of changes in these parameters during long-term follow-up, and on the tolerability of repeated rituximab (RTM) therapy cycles.

Subjects And Methods: RTM was given to 97 patients with high activity of SLE refractory to treatment with glucocorticosteroids (GCS) and cytostatics. The follow-up lasted 18 (12-36) months.

[Advances and prospects in the treatment of systemic lupus erythematosus].

Aim: To reveal the priorities of Russian rheumatology to develop treatment options for systemic lupus erythematosus (SLE).

Materials And Methods: The data available in the Russian and foreign literature, the archives and publications by the researchers of the Institute of Rheumatology on systemic lupus erythematosus in 1958 to 2008 were analyzed.

Results: Analyzing the literature references has ascertained that the researchers of the Institute of Rheumatology, Russian Academy of Medical Sciences, have initiated studies to develop therapy methods for SLE since 1958.

[Human cerebellar dimensions as evidenced by magnetic resonance imaging].

Magnetic resonance imaging data were analyzed in 340 patients (224 males, 116 females) aged 20 to 80 years. The dimensions of cerebellum were estimated on its standards sections. A relationship was found between the cross dimension of the cerebellum and the craniometric indices.

The weight and linear dimensions of the human cerebellum.

Data on the weights and linear dimensions of the cerebella from the corpses of 80 women and 140 men aged 20-90 years were studied, using standard methods for statistical data analysis. A relationship was found between differences in the weight and the linear dimensions of the cerebellum and differences in skull size. Cerebellar weight and transverse dimensions were greater in males than in females.

[Mass and linear dimensions of the human cerebellum].

The analysis of the data on mass and linear dimensions of human cerebellum, obtained at autopsy from 80 females and 140 males aged 20 to 90 years, was performed using the standard statistical methods of data processing. The mass and linear dimensions of the cerebellum were found to correlate with the dimensions of the skull. Mass and transverse dimension of cerebellum in males were larger than those in females.

[Synchronous programmed intensive therapy of patients with severe rheumatoid arthritis].

Aim: To evaluate efficiency and safety of intensive treatment program (synchroneous plasmapheresis, large-dose methotrexate and methypred) for patients with severe rheumatoid arthritis (RA).

Material And Methods: 45 patients with highly active and progressive RA, systemic symptoms, corticosteroid dependence who had intolerance to standard therapy or had not responded to it were divided into 2 comparable groups. 25 patients of group 1 for a month got 6 plasmapheresis procedures with synchroneous intravenous injection of 40 mg of methotrexate and 250 mg of methypred.

[Classification of the avian summer population of the Western Siberian plain].

The proposed classification system reflects the difference between the three population systems: unbuilt land, built-up land, and aquatic-semiaquatic communities. Two superorder groups--north and median--further divided into types were recognized in each of the systems. Most types are divided into subtypes, classes, and subclasses (and sometimes genera of the population).

[Treatment with megadoses of dexaven (dexamethasone) versus methypred (6-methylprednisolone) of patients with rheumatoid arthritis].

Aim: To compare clinical effectiveness and tolerance of methylprednisolone (methypred) and dexamethasone (dexaven) in patients with rheumatoid arthritis (RA), to estimate side effects and complications rate.

Materials And Methods: The trial included 31 patients with seropositive RA (27 females, 4 males) stage II and III. Dexaven pulse-therapy was given to 16 patients in a dose 2 mg/kg for 3 days, 15 patients received methypred in a classic dose 1000 mg for 3 days.

[Synchronous intensive treatment for patients with systemic lupus erythematosus having poor life prognosis].

Synchronous intensive treatment (SIT) involving two-stage programmed use of pulse therapy (PT), plasmapharesis (P) or hemosorption with methylprednisolone and cyclophosphamide was performed in 56 patients with systemic lupus erythematosus (SLE). All the patients were found to have a combination of factors showing a poor life prognosis: the onset of SLE in adolescence or youth (52%), nephritis (70%), arterial hypertension (54%), cerebropathy (50%), generalized vasculitis (34%), cryoglobulinemia (66%). After a year therapy, remission and the minimum progression were observed in 19.

[The use of the cephalosporin antibiotic Zinnat under polyclinic conditions in treating patients with bronchopulmonary infections].

The cephalosporin antibiotic zinnat was given to 171 outpatients with bronchopulmonary infections. Pneumonia patients received 500 mg, patients with acute bronchitis or exacerbation of chronic bronchitis 250 mg twice a day. The recovery was registered in 97.

[A comparative study of the expression of activation markers on T-lymphocyte subpopulations in different forms of bronchial asthma].

In this study we investigated a phenotype of intact and PHA-stimulated T-lymphocytes from peripheral blood of patients with allergic and nonallergic asthma. Expression of the activation markers (CD25, CD71, HLA-DR) on subsets of T-lymphocytes (CD4+ and CD8+) was determined using double-colour flow cytometry. It was found that nonallergic patients had increased percentages of CD4+CD25+, CD8+CD25+, CD4+HLA-DR+, CD8+HLA-DR+ cells.

[The combined intensive therapy of rheumatoid arthritis with systemic manifestations].

The efficacy of pulse therapy in combination with hemosorption or plasmapheresis, pulse therapy without extracorporeal treatment and methotrexate has been compared for 40 patients with rheumatoid arthritis (RA) with extra-articular manifestations. All kinds of intensive treatment were effective. Extracorporeal methods and pulse therapy relieved extra-articular symptoms.

[Splenic perfusion in the combined treatment of patients with systemic lupus erythematosus].

Twenty patients suffering from severe systemic lupus erythematosus (SLE) underwent 52 sessions of splenoperfusion (SP) by means of extracorporeal perfusion of the patient's blood through isolated porcine spleen. It got prepared directly before the perfusion. The organ was obtained from a healthy animal in sterile conditions, washed from the blood after cannulation of the artery and vein.

[Effects of vitamins A, E, C and P on intensity of blood coagulation in experimental animals].

In experiment on white rats it was shown that preventive 12-day administration of vitamins A, E, C, P decreases the death rate of animals with exogenous thromboplastinemia and reduces hemocoagulative changes, microcirculation disorders, destructive changes of functionally active elements of inner organs. The protective effect of the above vitamins combination in thromboplastinemia is promoted by hypoactivity of platelet aggregation, by low thromboplastic activity of erythrocytes, by limited destruction of vascular endothelium.

[Pulse therapy with methylprednisolone and cyclophosphamide in systemic juvenile rheumatoid arthritis: the results of an open, parallel, controlled, randomized, 12-month study].

The treatment for systemic JRA is among actual problems of pediatric rheumatology. To evaluate the effectiveness of pulse therapy (PT) with methylprednisolone 25-30 mg/kg/day for 3 consecutive days combined with cyclophosphamide 0.4-0.

[A comparative evaluation of combined immunocorrective therapy in rheumatoid arthritis with systemic manifestations (joint Soviet-Polish research)].

Thirty-two patients with rheumatoid arthritis were included in the trial. Each of them was assigned to one of the 4 groups comparable by the main features. Each group entered 8 patients.

[The prediction of thrombosis development in patients with systemic lupus erythematosus: the role of antibodies to cardiolipin].

In patients with systemic lupus erythematosus (SLE), the synthesis of antibodies to cardiolipin (A-CL) is associated with the development of venous and arterial thromboses localized in minor and middle-sized vessels, in the venous system and capillaries. The determination of various A-CL isotypes may be used to predict thromboses in SLE patients. Overall 210 patients (185 women and 25 men) with a verified diagnosis of SLE were examined.

[Clinico-immunological characteristics of patients with systemic lupus erythematosus and cryoglobulinemia].

Sixty patients with systemic lupus erythematosus (SLE) were examined: 40 patients with cryoglobulinemia and 20 patients without it. Cryoglobulinemia was observed in patients with SLE, as a rule, in the acute course of the disease ending in renal affection. Cryoglobulinemia in SLE was accompanied by the phenomenon of generalized vasculitis in the form of skin and mucosa lesions with ulcero-necrotic changes and affections of the central and peripheral nervous system and the kidneys.