A novel N95 respirator with chitosan nanoparticles: mechanical, antiviral, microbiological and cytotoxicity evaluations.

Background: It is known that some sectors of hospitals have high bacteria and virus loads that can remain as aerosols in the air and represent a significant health threat for patients and mainly professionals that work in the place daily. Therefore, the need for a respirator able to improve the filtration barrier of N95 masks and even inactivating airborne virus and bacteria becomes apparent. Such a fact motivated the creation of a new N95 respirator which employs chitosan nanoparticles on its intermediate layer (SN95 + CNP).

In vivo Hemostatic Activity of Jatropha mollissima: A Triple-Blinded, Randomized, Controlled Trial in an Animal Model.

Objective: The objective of this study was to evaluate the hemostatic activity of the sap from (Pohl) Baill. in rats.

Materials And Methods: Twenty-four Wistar rats were randomized into four groups ( = 6): the JM25 and JM40 groups were treated with ethanolic extract from the sap of , in a concentration of 25 and 40 mg·mL, respectively; the MO group was treated with Monsel's solution and the control group SC with a 0.

Chemodiversity and Antibacterial Activity of the Essential Oil of Leaves of Croton argyrophyllus.

The Croton argyrophyllus leaf essential oil has anti-inflammatory, antioxidant, cytotoxic among other activities. However, there are chemical composition variations in the literature. This work reports the first study of the intraspecific chemical variation of C.

N-Acetyl-D-Glucosamine-Loaded Chitosan Filaments Biodegradable and Biocompatible for Use as Absorbable Surgical Suture Materials.

The aim of this study was to prepare chitosan (CS) filaments incorporated with N-acetyl-D-Glucosamine (GlcNAc), using the wet spinning method, in order to combine the GlcNAc pharmacological properties with the CS biological properties for use as absorbable suture materials. The filaments were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), uniaxial tensile testing, in vitro biodegradation, and through in vitro drug release and cytotoxicity studies. It was observed that the addition of GlcNAc did not alter the morphology of the filaments.

Evaluation of behavioral and pharmacological effects of Hedyosmum brasiliense and isolated sesquiterpene lactones in rodents.

Ethnopharmacological Relevance: Hedyosmum brasiliense Miq. (Chloranthaceae) is an essential Brazilian species largely found in the Atlantic Forest. It is popularly known as "cidrão" and in folk medicine, this aromatic species is widely used as a calmative/tranquilizer and to treat sleep disorders.