Excisional biopsy, axillary node dissection and definitive radiotherapy for Stages I and II breast cancer.

From 1977 to 1982, 189 patients with clinical Stage I and II breast cancer underwent excisional biopsy and axillary node dissection followed by definitive radiotherapy at the University of Pennsylvania. One hundred and nine patients had T1 lesions and 80 had T2 lesions. Histologically negative nodes were found in 136 patients (72%) and histologically positive nodes in 53 patients.

Multimodality therapy of localized unresectable pancreatic adenocarcinoma.

Eighty-eight patients with localized unresectable carcinoma of the pancreas were treated at Thomas Jefferson University Hospital between 1974 and 1981. Four treatment regimens were used which were sequential modifications of the technique based on the experience in the preceding group of patients. Each treatment changed the course of the disease, and as patterns of failure were identified, the treatment was altered to deal with them.

Breast cancer in young women treated definitively with radiotherapy. An early report.

Between 1977 and 1982, 34 breast cancers in 33 women aged less than or equal to 35 years were treated with primary radiotherapy following excisional biopsy and axillary lymph node dissection. The records of these cases were reviewed and compared to 156 women greater than age 35 with 157 breast cancers treated similarly during the same time period. Analysis of these cases was limited to patients with invasive cancers who were AJC Stages I or II.