Publications by authors named "Solene Lartigue"
J Mol Med (Berl)
January 2020
Article Synopsis
- Preeclampsia (PE) is a serious pregnancy condition that occurs due to improper trophoblast cell invasion affecting blood circulation between the mother and fetus.
- CK2, an enzyme involved in cellular processes, was found to be more active during early pregnancy and its inhibition negatively impacted trophoblast cell functions essential for healthy development.
- The study observed that CK2 activity increases in placentas from PE patients and in PE mouse models, suggesting its role in supporting feto-maternal circulation, potentially indicating a compensatory response to the challenges in PE.
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