Determinants of Chikungunya and O'nyong-Nyong Virus Specificity for Infection of and Mosquito Vectors.

Mosquito-borne diseases caused by viruses and parasites are responsible for more than 700 million infections each year. and are the two major vectors for, respectively, malaria and arboviruses. mosquitoes are the primary vector of just one known arbovirus, the alphavirus o'nyong-nyong virus (ONNV), which is closely related to the chikungunya virus (CHIKV), vectored by mosquitoes.