Effect of Repeated Exposure to Sevoflurane on Electroencephalographic Alpha Oscillation in Pediatric Patients Undergoing Radiation Therapy: A Prospective Observational Study.

Background: Pharmacological tolerance is defined as a decrease in the effect of a drug over time, or the need to increase the dose to achieve the same effect. It has not been established whether repeated exposure to sevoflurane induces tolerance in children.

Methods: We conducted an observational study in children younger than 6 years of age scheduled for multiple radiotherapy sessions with sevoflurane anesthesia.

Molecular characterization of methicillin-resistant Staphylococcus aureus isolates reveals the spreading of a new clone in Buenos Aires City.

We performed a hospital-acquired methicillin-resistant Staphylococcus aureus molecular study in Buenos Aires city. Four clones were found harboring the transposable elements Tn4001 and Tn5405 and the erythromycin resistance determinants ermA and mef(E). Of the isolates, 73% belonged to a clone found previously in the city of Córdoba, which showed an epidemic behavior initially attributed to the widely disseminated South American clone.