[Using L-carnitine to improve the adaptation of young athletes to physical load and the correction of stress-induced cardiomyopathy].

The mechanisms of L-carnitine action and ergogenic pleiotropic effects of drugs, which play important role in sports medicine are described. Results of a comparative, parallel-group randomized clinical trial of L-carnitine (Elkar, PikFarma) in young athletes (football players, walkers) are reported. Elkar increases the body adaptation to physical stress and has a pronounced therapeutic effect in athletes with stress-induced cardiomyopathy by reducing the representation of potentially dangerous arrhythmia (sinus bradycardia less than 2 - 5 centile, 2nd degree atrioventricular block type II, T-wave inversion in more than 2 leads, and/or ST segment depression) and severity of benign ECG disturbances and hemodynamic changes, and decreasing the concentration of biochemical markers of myocardial damage (troponin, natriuretic peptide, creatine phosphokinase MB fraction) and cortisol.

[Functional morphology of nucleated erythrocytes during hypoxia (in vitro experiments)].

Changes in morphologic and functional properties of nucleic erythrocytes were observed during experimental hypoxia in vitro. It has been shown that erythrocytes volume and nuclei volume decrease in oxygen concentration of 1.76-4.