Publications by authors named "Solange Rodrigues Valle"
Article Synopsis
- Chronic urticaria (CU) patients show a significant interest in using mobile apps to monitor their disease activity and control, with over half expressing high levels of interest in app usage.
- A study involving 1841 CU patients from 17 countries found that a majority have chronic spontaneous urticaria (CSU) and are predominantly female and urban-dwelling.
- The findings suggest that the development of tailored and expert-validated apps for different urticaria types could enhance disease management and inform future research efforts.
Background: Cold urticaria (ColdU), that is, the occurrence of wheals or angioedema in response to cold exposure, is classified into typical and atypical forms. The diagnosis of typical ColdU relies on whealing in response to local cold stimulation testing (CST). It can also manifest with cold-induced anaphylaxis (ColdA).
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- TempTest® employs the Peltier effect to diagnose cold and heat urticaria by measuring temperature variations in patients.
- A study analyzed medical records of 12 patients from Rio de Janeiro who had a history of temperature-related urticaria, testing their reactions to temperature provocations using TempTest®.
- Results indicated that 3 patients had heat urticaria and 9 had cold urticaria, with the test proving effective in diagnosing these conditions and aiding in patient safety.
Hereditary angioedema (HAE) is an autosomal dominant disease mostly due to the deficiency of C1 inhibitor (C1-INH). HAE with normal C1-INH was first described in 2000 and associated with mutations in the coagulation factor XII in 2006. Both diseases are associated with high bradykinin production, resulting in increased vascular permeability.
View Article and Find Full Text PDFBackground: Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH) is a rare condition with clinical features similar to those of HAE with C1-INH deficiency. Mutations in the F12 gene have been identified in subsets of patients with HAE with normal C1-INH, mostly within families of European descent.
Objectives: Our aim was to describe clinical characteristics observed in Brazilians from 42 families with HAE and F12 gene mutations (FXII-HAE), and to compare these findings with those from other populations.