Publications by authors named "Solange Ngazoa Kakou"
Background: To meet the WHO target of eradicating yaws by 2030, highly sensitive and specific diagnostic tools are needed. A multiplex Treponema pallidum-Haemophilus ducreyi loop-mediated isothermal amplification (TPHD-LAMP) test holds promise as a near-patient diagnostic tool for yaws and H ducreyi. We conducted a prospective evaluation in Cameroon, Côte d'Ivoire, Ghana, and the Republic of the Congo to determine the diagnostic accuracy of the TPHD-LAMP test, as well as to assess its acceptability, feasibility, and cost.
View Article and Find Full Text PDFArticle Synopsis
- Integrated approaches to mapping skin Neglected Tropical Diseases (NTDs) may optimize resource allocation, but extensive data covering multiple endemic countries was previously lacking.
- Between March 2021 and March 2023, integrated case searches were conducted in Cameroon, Côte d'Ivoire, and Ghana, screening over 61,000 individuals for various skin conditions including yaws and other NTDs.
- The findings revealed that 18.6% of those screened had skin lesions, with the majority being children; yaws was confirmed in a varying proportion of cases across the three countries, while scabies and fungal infections were the most commonly diagnosed conditions.
Article Synopsis
- - Yaws, caused by the bacterium Treponema pallidum ssp. pertenue, is a major health issue in tropical West Africa and the South Pacific, particularly impacting children in areas lacking hygiene and sanitation.
- - A study in Ghana, Cameroon, and Côte d'Ivoire found diverse beliefs about yaws transmission among locals, with many attributing it to germs or contaminated water, while some linked it to witchcraft, and a low percentage recognized person-to-person contact as a method of transmission.
- - Most participants preferred seeking care from hospitals or healthcare professionals if diagnosed with yaws, but there was a significant reliance on traditional healers in Côte d'Ivoire, highlighting the necessity for increased community education and awareness
phages Carena and JoYop were isolated from water samples in Abidjan (Cote d'Ivoire). Their genomes comprise 39,283 and 169,193 bp, encoding 44 and 246 predicted genes, respectively. Carena shares 93.
View Article and Find Full Text PDFIntroduction: Yaws, caused by the bacterium subsp. is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal.
View Article and Find Full Text PDFArticle Synopsis
- Lassa fever has not previously been reported in Côte d'Ivoire.
- A study analyzed serum samples from 2015 to 2018 collected during dry seasons.
- The analysis revealed a fatal case of Lassa fever in the Bangolo District in 2015.
Four major genotypes of Hepatitis E virus (HEV) have been documented worldwide (1-4) with genotypes 1 and 2 found in human in Sub-Saharan Africa. Human Hepatitis cases due to HEV genotype 3 and 4 are zoonotic with various animal identified as possible reservoirs. Recently, HEV genotype 3 was found in pigs and human beings in West Africa, which may change the epidemic in human.
View Article and Find Full Text PDFThe lytic Escherichia coli siphophage BRET was isolated from a chicken obtained at a local market in Abidjan, Côte d'Ivoire. Its linear genome sequence consists of 59,550 bp (43.4% GC content) and contains 88 predicted genes, including 4 involved in archaeosine biosynthesis.
View Article and Find Full Text PDFThe lytic phage Ebrios was isolated from a water sample collected in Ebrie Lagoon on the Adiopodoumé River in Abidjan (Republic of Côte d'Ivoire, West Africa). The linear genome of this family member contains 39,752 bp, has a G+C content of 52.9%, is composed of 53 open reading frames, and is related to the phage IME15.
View Article and Find Full Text PDF