Changes in and the relationships between alpha-klotho, oxidative stress, and systemic inflammation in cigarette smokers.

Background: Although smoking is known to accelerate aging, the mechanisms by which this occurs have not been fully clarified. Serum-soluble α-Klotho (sαKl), antiaging, anti-inflammatory, and developing resistance to oxidative stress properties are known.

Aim: This study aimed to determine the relationship between cigarette smoking, sαKl (antiaging hormone), inflammation, and oxidative stress.

Effects of hyaluronic acid and chondroitin sulfate on acute radiation proctitis in rats.

Background: This study was designed to investigate the prophylactic and therapeutic effects of hyaluronic acid and chondroitin sulfate combination (HA/CS) on a model of acute radiation proctitis.

Methods: Rats were divided into five groups: SHAM; irradiation (IR) + saline (1 mL for 5th and 10th day); IR + HA/CS (1 mL for 5th and 10th day). A single fraction of 17.

Colonic Obstruction Secondary to Phytobezoar Caused by Vitex Agnus-Castus Seeds: A Case Report.

Plant seeds of Vitex agnus-castus (chaste berry) are known for benefits in reproductive health and also reduce bloating, depression, headache, and constipation. Plant seeds are a rare cause of phytobezoars. Bezoar is a formation of mass by piling up of material that is ingested but not digested or partially digested at any level of the gastrointestinal tract.

Is Histopathological Evaluation of Hernia Sacs Necessary?

Background: Our aim was to investigate the pathologies in the hernia sac in adults, and the frequency of malignancy as well as to confirm the necessity of maintaining the current applications in histological examination of the hernia sac.

Methods: Patients who were operated for hernia in our clinic from 2013 to 2019 were included in the study. Patient data were evaluated retrospectively.

Thiol-disulfide homeostasis in breast cancer patients.

Objective: The aim of our study is to assess thiol-disulfide homeostasis (TDH), which is a biomarker of systemic oxidative stress, in breast cancer patients.

Materials And Methods: Thirty-seven breast cancer patients and 31 age-matched healthy volunteers were enrolled in this study. Serum native thiol, disulfide, and total thiol levels and disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol ratios were analyzed using a novel colorimetric method.

The influence of Body Roundness Index on sensorial block level of spinal anaesthesia for elective caesarean section: an observational study.

In this prospective trial, we investigate the effectiveness of maternal Body Roundness Index in predicting the spread of spinal anaesthesia and vasopressor requirement in parturients receiving spinal anaesthesia during the elective caesarean section. We prospectively enrolled 175 parturients. Spinal anaesthesia performed with 10 mg 0.

Visceral Adiposity Index Levels in Patients with Hypothyroidism.

Objective: To assess visceral adiposity index (VAI) as a sign of cardio-vascular diseases (CVD) in hypothyroidism patients and to compare CVD risks in overt or subclinical hypothyroidism patients.

Materials And Methods: Sixty-eight hypothyroidism patients (29 with overt and 39 with subclinical hypothyroidism) and 33 age- and gender-matched control patients were included. VAI levels were calculated with the following formula: (waist circumference (WC)/[36.

Evaluation of 25-Hydroxyvitamin D Levels in Central Anatolia, Turkey.

Background/aim: The aim of this study is to evaluate serum 25-hydroxyvitamin D levels measured within one year at an Education and Research Hospital in Turkey to identify vitamin D insufficiency/deficiency (which is very commonly seen in the society) and to provide a current approach to treatment management.

Materials And Methods: This retrospective descriptive study was carried out by examining the data relating to 35,667 individuals.

Results: Of the individuals participating in the study, 94.

The effects of smoking cessation on visceral adiposity index levels.

Background: : Known to cause important metabolic disturbances, weight gain becomes a major health problem after smoking cessation. Visceral adiposity index (VAI) is becoming increasingly popular in the detection of cardiometabolic risks in several disorders and general population. Here, we aimed to investigate the effects of quitting smoking on VAI levels.

Effects of smoking on thiol/disulfide homeostasis.

Objective: Cigarette smoking is an important risk factor for many diseases. This study aimed to evaluate whether cigarette smoking is associated with changes in the thiol/disulfide homeostasis (TDH), a novel biomarker of systemic oxidative stress.

Patients And Methods: Eighty-four smokers and 86 non-smoking healthy volunteers were enrolled.

The effects of smoking on neutrophil/lymphocyte, platelet/ /lymphocyte ratios.

Objective: The aim of this study was to compare the Neutrophil to Lymphocyte ratio (NLR), Platelet to Lymphocyte ratio (PLR) and Mean Platelet Volume to Platelet (MPV/Plt) ratio of smokers and non-smokers.

Methods: Two hundred smokers and two hundred non-smoking healthy volunteers were enrolled in this study. Sociodemographic data and hematologic parameters of all patients were recorded.

Efficacy and Safety of ATG-Fresenius as an Induction Agent in Living-Donor Kidney Transplantation.

Background: Induction therapy is mostly recommended for deceased-donor transplantation, whereas it has some controversies in live-donor transplantation. In this study, we described the outcomes of live-donor renal transplant recipients who received ATG-Fresenius (ATG-F) induction.

Methods: Live-donor transplantations in patients over 18 years old with ATG-F induction between 2009 and 2015 were included.

A rare manifestation of achalasia: huge esophagus causing tracheal compression and progressive dyspnea.

Achalasia is a primary esophageal motility disorder characterized by the absence of primary peristalsis and a failure of the lower esophageal sphincter to relax, resulting in a dilated esophagus. Dysphagia is the classic and most common symptom. Respiratory obstruction due to tracheal compression caused by a massively dilated esophagus is a very rare but fatal complication.

The value of diffusion-weighted magnetic resonance imaging in the differential diagnosis in diffuse bowel wall thickening.

Background/aims: We aimed to investigate the value of diffusion-weighted magnetic resonance imaging in the differentiation of benign-malignant diffuse bowel wall thickening (scirrhous colon carcinoma) and to discuss the diagnostic importance and potential use of apparent diffusion coefficient measurements.

Materials And Methods: A total of 41 patients (32 males, 9 females; mean age, 57 years) with diffuse bowel wall thickening diagnosed on computed tomography were included in this study. The magnetic resonance imaging was performed on a 1.

The role of diffusion-weighted examination in non-polyploid gallbladder malignancies: A preliminary study.

Background/aims: The aim of the present study was to investigate the diagnostic value of diffusion-weighted magnetic resonance imaging in gallbladder malignancies, which are typically diagnosed during surgery because the radiologic findings are similar to those of cholecystitis-caused diffuse thickening of the gallbladder wall.

Materials And Methods: Seven patients with gallbladder malignancies and nine patients with benign gallbladder pathology were included in this study. In one of the patients with a malignancy, a lesion was determined on the porcelain gallbladder; in another patient, acute myeloblastic leukemia had infiltrated the gallbladder, causing the diffuse wall thickening.

Abdominal cocoon syndrome: preoperative diagnostic criteria, good clinical outcome with medical treatment and review of the literature.

Sclerosing encapsulating peritonitis, or abdominal cocoon syndrome, was described firstly in young adolescent girls. It is characterized by a thick fibrotic peritoneum that wraps the bowel in a concertina-like fashion with some adhesions. We report a man with intermittent intestinal obstruction and an abdominal cocoon encasing the small bowel.

Abdominal wall endometrioma: ultrasonographic features and correlation with clinical findings.

Background: The diagnosis of abdominal wall endometrioma (AWE) is often confused with other surgical conditions. Certain factors relating to knowledge of the clinical history of the disease make correct diagnosis and treatment difficult.

Aims: To present the clinical findings and ultrasonographic (US) features of AWE with special emphasis on size-related features.

A horseshoe kidney from a live donor as a renal transplant: case report.

Objectives: This case report presents our experience regarding a horseshoe kidney from live donor to be used as a renal transplant.

Materials And Methods: The recipient was a 48-year-old man with chronic renal failure owing to hypertension who had been on hemodialysis for 2 years. The donor was his 43-year-old sister who had an uncomplicated horseshoe kidney with negative results on a urinalysis.

Transverse colon diverticulitis with calcified fecalith.

Left colonic diverticula are common in Western populations, whereas right colonic diverticulosis primarily occurs in Oriental populations. Diverticulitis of the transverse colon is very rare, with very few cases reported in the literature. Herein, we report a case of transverse colon diverticulitis caused by a calcified stone in a 69-year-old female.

Spousal versus living unrelated renal transplantation: a retrospective analysis of allograft outcomes.

Objective: To compare the outcomes of spousal and living unrelated donor (LUD) allografts.

Patients And Methods: The 378 ABO-compatible living and cadaveric kidney transplantations between February 2005 and August 2010 included 25 wife-to-husband (group 1), 15 husband-to-wife (group 2), and 20 LUD cases (group 3). Donor nephrectomy was performed by open surgery.

Long-term outcomes of kidney transplants with multiple renal arteries: a retrospective study.

Objective: The aim of this study was to investigate whether kidney transplantations performed using grafts with multiple arteries negatively affected renal function or increased the risk of vascular or urologic complications.

Methods: Among 249 kidney transplant patient followed for at least 1 year between 2000 and 2005, we retrospectively evaluated their donor renal artery anatomy to compare postoperative vascular and urologic complications: creatinine clearance at 1, 2, and 5 years, as well as graft survival at 3 and 5 years.

Results: While 214 (85.

Use of kidney donors with hepatitis B, hepatitis C, or brain tumor: a single-center experience.

Introduction: With the rapid increase in the number of patients on the waiting lists, the idea of using organs from donors who were previously classified as "marginal" has emerged. The aim of this study was to evaluate the clinical outcomes of the patients who received kidneys from donors with hepatitis B, hepatitis C, or brain tumors.

Patients And Method: Between 2003 and 2010, 27 transplantations were performed from donors with hepatitis B, hepatitis C or brain tumors between 2003 and 2010.

What kind of changes occurred in clinical characteristics of deceased kidney donor recipients after national allocation system in Turkey? A single-center retrospective analysis.

Objective: Clinical characteristics of recipients of deceased donor renal transplantations were evaluated in the period before versus after implementation of The National Allocation System (NAS).

Patients And Methods: We evaluated retrospectively clinical profiles of the 42 after NAS (June 2008-December 2010) versus 42 consecutive deceased donor renal transplantation patients before NAS. Patient and graft survival rates were assessed using the Kaplan-Meier method; graft function was assessed based on creatinine clearance with the Cockcroft Gault equation.

Effects of IgM-enriched immunoglobulin and fluid replacement on nerve conduction velocity in experimental sepsis.

Background: Neuromuscular abnormalities in sepsis, termed critical illness polyneuropathy (CIP), have been suggested to be induced by inflammatory mechanisms and/or relative hypovolemia. CIP is characterized by early electrophysiological findings before the clinical symptoms. This study aimed to investigate the effect of intravenous immunoglobulin (IVIG) and volume replacement therapies on the possible nerve conduction velocity (NCV) alterations in the early phase of experimental sepsis.