Analysis of factors influencing target PASI responses and side effects of methotrexate monotherapy in plaque psoriasis: a multicenter study of 1521 patients.

Methotrexate (MTX) is commonly used as first-line systemic treatment agent in psoriasis. We aimed to evaluate the clinical characteristics and treatment responses of patients with psoriasis undergoing MTX monotherapy. Data from adult patients with plaque psoriasis who received MTX monotherapy for at least 3 months between April 2012 and April 2022 were retrospectively evaluated in 19 tertiary care centers.

Real-life data over 36 weeks of guselkumab treatment in psoriasis patients: A single-center study from Turkey.

Background: Psoriasis is an important health problem responsible for morbidity and workforce loss. In recent years, anti-IL-23 drugs have become essential in psoriasis treatment.

Objectives: This study aimed to investigate the efficacy and safety of guselkumab therapy, recently used in Turkey, by examining real-life data over 36 weeks.

Quercetin-loaded sodium alginate/collagen/h-boron nitride potential wound dressings prepared using the Box-Behnken experimental design.

Background/aims: Natural and synthetic biocompatible polymers have received significant attention in the pharmaceutical industry due to their rapid and effective healing properties in the wound healing process. The aim of this study was to optimize the extraction of onions, the preparation of sodium alginate/collagen/hydrogen boron nitride (NaAlg/Col/h-BN) membranes using the Box-Behnken experimental design, and determine the optimal conditions for quercetin release. The study also aimed to investigate the antimicrobial and antioxidant activities of the prepared membranes and their therapeutic properties.

Tibial Tuberosity Rotation in Patients With Patellar Instability Versus Age- and Sex-Matched Controls.

Background: Several methods have been described to measure external rotation of the tibial tuberosity; all use femoral landmarks.

Purpose: To develop reproducible tibial-based methods to measure external rotation of the tibial tuberosity in patients with patellar instability.

Study Design: Cross-sectional study; Level of evidence, 3.

Clinical outcomes of COVID-19 in patients with chronic diseases.

Objective: This study was carried out to evaluate the clinical outcomes of patients having chronic diseases (CD) and COVID-19 infection.

Methods: The study was carried out retrospectively by including 1.516 patients with CDs who applied to two education and research hospitals between June 01, 2021, and August 01, 2021, and were diagnosed with COVID-19.

Advances in organic photovoltaic cells: a comprehensive review of materials, technologies, and performance.

This paper provides a comprehensive overview of organic photovoltaic (OPV) cells, including their materials, technologies, and performance. In this context, the historical evolution of PV cell technology is explored, and the classification of PV production technologies is presented, along with a comparative analysis of first, second, and third-generation solar cells. A classification and comparison of PV cells based on materials used is also provided.

Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study.

Objectives: In this study covering all of Turkey, we aimed to define cutaneous and systemic adverse reactions in our patient population after COVID-19 vaccination with the Sinovac/CoronaVac (inactivated SARS-CoV-2) and Pfizer/BioNTech (BNT162b2) vaccines.

Methods: This prospective, cross-sectional study included individuals presenting to the dermatology or emergency outpatient clinics of a total of 19 centers after having been vaccinated with the COVID-19 vaccines. Systemic, local injection site, and non-local cutaneous reactions after vaccination were identified, and their rates were determined.

Association of blood groups on the risk of COVID-19 infection, morbidity, and mortality.

Objective: We aimed to compare the effects of blood groups and Rh factor on the development of coronavirus-19 disease (COVID-19) with all aspects such as clinical course, inflammatory parameters, and organ-specific biochemical parameters with a significant number of patients.

Methods: This multicenter study was carried out retrospectively on 3551 patients hospitalized with the diagnosis of COVID-19 and whose blood groups were recorded during the time of hospitalization. As control groups, 22133 individuals' medical data who were admitted to the blood bank affiliated with our hospitals during the last year was used.

Evaluation of the causes affecting the development of pruritus in patients with peritoneal dialysis.

Background: Several factors play a role in the pathogenesis of pruritus in uremic patients. The pathophysiology is complex and many factors have been identified in these patients. The aim of this study was to investigate the presence, severity, and possible causes of pruritus in patients with peritoneal dialysis (PD) .

Endovascular Treatment for Near Occlusion of the Internal Carotid Artery : 30-Day Outcome and Long-Term Follow-Up.

Background: The treatment strategy and the correct incidence of near occlusion (NO) of the internal carotid artery (ICA) is still controversial. In routine radiological imaging NO can easily be misdiagnosed as complete occlusion and there is no consensus on the standard treatment strategy.

Purpose: To present our perioperative and long-term follow-up results of ICA NO patients treated with carotid artery stenting (CAS).

Effect of long-term Helicobacter pylori infection on growth of children: a cohort study.

Background: The effects of Helicobacter pylori (H. pylori) infection on growth are a controversial issue. We investigated the effects of long-term H.

Mean platelet volume in children with Reye-like syndrome.

Reye-like syndrome (RLS) is considered to be a systemic disorder in which the cytokine storm plays a major role. Mean platelet volume (MPV), which is commonly used as a measure of platelet size, indicates the rate of platelet production and platelet activation. We aimed to study MPV in children with RLS.

Iron Deficiency Anemia among Hospitalized Children in Konya, Turkey.

The aim of this study was to investigate the characteristics of our hospitalized patients with the diagnosis of iron deficiency anemia (IDA) and effects of the IDA prevention project of the Turkish Ministry of Health which was started in 2004. The recommended dose of prophylactic iron supplementation was 1-2 mg/kg/day. The files of 1519 patients who were hospitalized to Konya Education and Research Hospital Pediatrics Clinic were reviewed.

Posterior reversible encephalopathy syndrome in children: report of three cases.

Purpose: Posterior reversible encephalopathy syndrome (PRES) is a condition characterized by varying degrees of headache, nausea, vomiting, visual disturbances, focal neurologic deficit, and seizures due to severe systemic hypertension. The knowledge of secondary hypertension in children is most commonly due to renal abnormalities, suggesting that the leading cause of PRES in childhood is renal diseases.

Methods: Three pediatric patients who developed PRES due to various underlying renal diseases were reviewed.

Successful Treatment of Antiepileptic Drug-Induced DRESS Syndrome with Pulse Methylprednisolone.

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but potentially life-threatening syndrome characterized by skin rash, fever, lymph node enlargement, and involvement of internal organs. It is most commonly induced by aromatic anticonvulsants and antibiotics. Nonaromatic anticonvulsants are rarely encountered as the causes of DRESS syndrome.

Comment on "Encryption and decryption of images with chaotic map lattices" [Chaos 16, 033118 (2006)].

In this paper, we comment on the chaotic encryption algorithm proposed by A. N. Pisarchik et al.

Attention to the eyes and fear-recognition deficits in child psychopathy.

The ability to recognise fear is impaired in people with damage to the amygdala and, interestingly, in adult psychopathy. Here we confirm that deficits in recognising fear exist in children with psychopathic traits. We show for the first time that, as with patients with amygdala damage, this deficit can be temporarily corrected by simply asking them to focus on the eyes of other people.

Epidemiology of hydrogen phosphide exposures in humans reported to the poison center in Mainz, Germany, 1983-2003.

Background: Poisonings with rodenticides containing hydrogen phosphide-releasing compounds may lead to deleterious organ dysfunction and death. Since data of hydrogen phosphide poisonings is limited to case reports/series, this study was intended to elucidate hydrogen phosphide poisonings based on a 20-year data collection.

Methods: Explorative data analysis of the Poison Center Mainz database looking for route of exposure, symptoms, and severity using the Poisoning Severity Score.