BONE RECONSTRUCTION IN THE TREATMENT OF TIBIAL HEMIMELIA: AN ALTERNATIVE TO AMPUTATION?

Objective: To evaluate the advantages and disadvantages of bone reconstruction and lengthening compared to amputation in the treatment of tibial hemimelia for patients and their families.

Methods: Systematic review of articles published in English and Portuguese between 1982 and 2022 in the MEDLINE, PubMed, Cochrane and SciELO databases. The variables of interest were: year of publication, sample characteristics, classification of tibial hemimelia according to Jones, treatment outcome and follow-up time.

Consensus of Spanish Society of Hospital Pharmacy on optimal medication therapy management of atopic dermatitis.

Aim: This study's aims are: 1) To use the Delphi method to determine the level of consensus among hospital pharmacists (HPs) as regards the factors involved in the current approach to patients with atopic dermatitis (AD); 2) To identify potential areas for improvement in hospital pharmacy in terms of dealing with patients with severe AD; and 3) To contribute to adequate pharmaceutical care for patients with AD by drawing up recommendations.

Methods: A two-round Delphi survey with participation from HPs from all over Spain. Three theme-based blocks were set out: 1) AD; 2) Management of patients with severe AD in the Hospital Pharmacy setting; and 3) Unmet needs (pathology, patient, treatment and management).

Color vision impairment in multiple sclerosis points to retinal ganglion cell damage.

Multiple Sclerosis (MS) results in color vision impairment regardless of optic neuritis (ON). The exact location of injury remains undefined. The objective of this study is to identify the region leading to dyschromatopsia in MS patients' NON-eyes.

Normative EMG values during REM sleep for the diagnosis of REM sleep behavior disorder.

Background: Correct diagnosis of rapid eye movement sleep behavior disorder (RBD) is important because it can be the first manifestation of a neurodegenerative disease, it may lead to serious injury, and it is a well-treatable disorder. We evaluated the electromyographic (EMG) activity in the Sleep Innsbruck Barcelona (SINBAR) montage (mentalis, flexor digitorum superficialis, extensor digitorum brevis) and other muscles to obtain normative values for the correct diagnosis of RBD for clinical practice.

Setting: Two university hospital sleep disorder centers.

Analysis of antibodies to surface epitopes of contactin-2 in multiple sclerosis.

Contactin-2 was recently identified as an autoantigen targeted by T-cells and autoantibodies in multiple sclerosis (MS). Here we analyzed the frequency of antibodies to contactin-2 (contactin-2-ab) by a cell-based assay in the serum from 105 MS patients and at least 5 years of follow-up (19 clinically isolated syndromes, 51 relapsing-remitting, 20 secondary-progressive, and 15 primary-progressive). Contactin-2-ab were detected in 4 (7.

Lateral saccular laryngeal cyst and unexpected asphyxial death.

We present the case of a 41-year-old man with a herniated saccular laryngeal cyst in the left cervical region who died unexpectedly at home from acute asphyxia. A few days before death the patient complained an obvious palpable swelling on the left side of the neck. The autopsy showed an oval-shaped mass originating on the wall of the larynx and herniating into the extralaryngeal region.

[Validating a patient-satisfaction questionnaire about professional advice received for minor illness in community pharmacies].

Objective: Analysing the evidence regarding the validity and reliability of a patient-satisfaction questionnaire about professional advice received for minor illness in Argentinean community pharmacies.

Methods: This was a descriptive, cross-sectional study. All patients or their caregivers who visited the pharmacies during the study period (March and April, 2006) and knew how to read and write were included.

Radical retropubic prostatectomy--report on 41 cases.

Anatomic radical retropubic prostatectomy is an effective method for long-term control of the prostatic carcinoma. In the current era of the anatomic prostatic surgery, blood loss is reduced, complication rate is low and control of the disease may be excellent. Some authors reported cancer-specific survival rate after the radical retropubic prostatectomy of 85-90% over the 10-year period and 82% over the 15-year period.

[Pharmacotherapeutic follow-up of patients in community pharmacies].

Objective: To analyse pharmacist intervention (PI) resulting from the implementation of the Dáder Pharmacotherapeutic Follow-Up Program (PFU).

Design: Descriptive study of the findings from the PFU program during the first year.

Setting: Community pharmacists in area of the College of Pharmacists of the Province of Cordoba (Argentina).

Quantitative analysis of metronidazole in intravenous admixture with ciprofloxacin by first derivative spectrophotometry.

Metronidazole in parenteral admixture with ciprofloxacin was analysed by first-derivative spectrophotometry using the zero-crossing technique of measurement. The procedure did not require prior separation steps. The method was found to be linear (r(2)>0.

Validation of a reversed-phase LC method for quantitative analysis of intravenous admixtures of ciprofloxacin and metronidazole.

The admixture ciprofloxacin-metronidazole is nowadays well known as a clinical tool when anaerobic organisms are involved. The stability of ciprofloxacin with metronidazole depends on several variables and this has been scarcely studied. Thus, the aim of this study was the search for a specific, precise and accurate method that would allow the quantification of ciprofloxacin in the presence of metronidazole.

[Control of respiratory monitoring in the critical patient].

This study of the safety of patients undergoing mechanical ventilation was undertaken to ensure correct ventilation and to find quality-control elements for patients and nursing staff. Differences in mode programming and ventilation parameters and their registry at the change of nursing shifts, and correct programming of the sensitivity and minimum minute volume alarms and maximum airway pressure alarms were examined. In a two-month period, 8 cross-sectional studies were made of G1 prevalence in each of three nursing shifts.