Publications by authors named "Sojomon Mathew"

The immune system presents significant obstacles to gene therapy, which has limited its use in treating many illnesses. New approaches are needed to overcome these problems and improve the effectiveness of gene therapy. This study explores several techniques to immune regulation within gene therapy, a cutting-edge discipline that aims to optimise results by fine-tuning the immune response.

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Article Synopsis
  • Neurological disorders are increasingly recognized as a significant health challenge due to oxidative stress and inflammation, which disrupt the brain's natural defenses and contribute to neurodegenerative diseases.
  • Recent advancements in the development of antioxidant compounds, including polyphenols, vitamins, and flavonoids, show promise for therapeutic applications in treating these disorders.
  • This review highlights the mechanisms of oxidative stress in neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, aiming to improve treatment strategies and enhance patient quality of life.
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Background: Depression is a global mental disorder, and traditional diagnostic methods mainly rely on scales and subjective evaluations by doctors, which cannot effectively identify symptoms and even carry the risk of misdiagnosis. Brain-Computer Interfaces inspired deep learning-assisted diagnosis based on physiological signals holds promise for improving traditional methods lacking physiological basis and leads next generation neuro-technologies. However, traditional deep learning methods rely on immense computational power and mostly involve end-to-end network learning.

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