Functional magnetic resonance imaging correlates of emotion recognition and voluntary attentional regulation in depression: A generalized psycho-physiological interaction study.

Background: Major depression is characterized by an impaired ability to evaluate and modify emotional responses as well as attention deficits, however the neural origins of these features are unresolved. The aim of the study was to investigate activation and functional connectivity changes during recognition and voluntary attentional regulation of emotion in 34 patients with major depressive disorder (MDD) compared to 35 controls.

Methods: We employed an fMRI task in which participants assessed the valence or the shape of emotional stimuli.

Magnetic resonance imaging in patients with borderline personality disorder: a study of volumetric abnormalities.

Volumetric abnormalities of the hippocampus and frontal cortex are of major interest in the study of borderline personality disorder (BPD). To our knowledge, no study has examined volumetric abnormalities in the hippocampal subregions (head, body, and tail). Our aims were to investigate hippocampal volumetric abnormalities as well as abnormalities in the gray and white matter of the frontal cortex, basal ganglia, and anterior cingulate cortex in BPD in a sample of BPD patients compared to healthy controls.