Publications by authors named "Sojiro Imai"
Several mechanisms strictly regulate polyamine concentration, and blood polyamines are excreted in urine. This indicates polyamine accumulation in renal dysfunction, and studies have shown increased blood polyamine concentrations in patients with renal failure. Hemodialysis (HD) may compensate for polyamine excretion; however, little is known about polyamine excretion.
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- The study investigates how standing after hemodialysis (HD) affects cerebral oxygenation in patients, particularly comparing those with and without diabetes mellitus (DM).
- Results show that cerebral regional oxygen saturation (rSO) significantly decreases from resting to standing, with a 6.8% drop in rSO specifically noted.
- The decrease in rSO is closely linked to diabetes presence, duration of HD, blood pressure changes, and indicates that patients with DM may experience more severe reductions in cerebral oxygenation after HD.
Article Synopsis
- The hepato-splanchnic circulation is crucial for oxygenating abdominal organs and compensating for blood volume loss during hemodialysis (HD), but assessing it clinically is challenging.
- A study involving 185 HD patients and 15 healthy controls found that hepatic regional oxygen saturation (rSO2) was significantly lower in HD patients compared to controls (56.4% vs. 76.2%).
- Factors such as body mass index (BMI), hemoglobin levels, cardiovascular disease history, mean blood pressure, and serum albumin concentration were linked to hepatic rSO2, indicating the need for further research on these parameters' impact during HD.
Background And Aims: The use of the psoas muscle mass index (PMI) using computed tomography (CT) has become a marker of interest to evaluate whole body muscle mass. However, in hemodialysis (HD) patients, reports about the clinical significance of psoas muscle evaluation are limited. We aimed to clarify the association between PMI and skeletal muscle mass index (SMI) using bioelectrical impedance analysis (BIA), and to investigate factors affecting PMI in HD patients.
View Article and Find Full Text PDFHemoglobin (Hb) is associated with cerebral oxygenation status owing to its important role of carrying oxygen to systemic tissues. However, data concerning the associations between Hb levels and cerebral regional oxygen saturation (rSO2) of hemodialysis (HD) patients is limited. We aimed to identify these associations to consider a target Hb level for renal anemia management.
View Article and Find Full Text PDFPatients with chronic kidney disease (CKD) are at risk for bone loss and sarcopenia because of associated mineral and bone disorders (MBD), malnutrition, and chronic inflammation. Both osteoporosis and sarcopenia are associated with a poor prognosis; however, few studies have evaluated the relationship between muscle mass and bone mineral density (BMD) in hemodialysis (HD) patients. The present study examined the association between skeletal muscle mass index (SMI) and BMD in the lumbar spine and femoral neck in HD patients.
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