Publications by authors named "Soji Kohyama"
Article Synopsis
- Left main coronary artery (LMCA) stenosis in coronary artery disease increases the risk of cardiac events, making it crucial to assess its role in ischemia.
- Noninvasive methods like myocardial perfusion scintigraphy (MPS) often provide unreliable results for multi-vessel disease, whereas fractional flow reserve from computed tomography (FFR-CT) shows promise in identifying functional ischemia.
- A case study of a 50-year-old woman demonstrated that FFR-CT effectively identified myocardial ischemia from LMCA stenosis, unlike MPS, highlighting its potential in diagnosing related cardiac issues in patients with right coronary artery hypoplasia.
Background: It is not known whether clopidogrel use in cytochrome P450 (CYP) 2C19 loss-of-function (LOF) carriers with high bleeding risk (HBR) contributes to adverse outcomes after percutaneous coronary intervention (PCI).
Methods and results: This retrospective observational study included 618 consecutive patients with available CYP2C19 polymorphism information who underwent PCI between September 2014 and August 2021. Patients with HBR (319 [52%] met the Academic Research Consortium definition) were divided into 2 groups according to P2Yinhibitor action, namely decreased (i.