Primary Sjogren's Disease Coexisting With Myasthenia Gravis: Two Distinct Autoimmune Diseases Successfully Treated With a Rituximab-Based Induction Regimen.

Primary Sjögren's syndrome (pSS) and myasthenia gravis (MG) are autoimmune diseases and are rarely reported in coexistence. MG is a chronic autoimmune neuromuscular disease where antibodies bind to acetylcholine receptors or to functionally related molecules in the postsynaptic membrane, weakening the skeletal muscles and causing diplopia, ptosis, and difficulty in breathing and swallowing. In this report, we discuss the case of a 43-year-old female patient who presented with dry eyes, weight loss, fatigue, ptosis, dysarthria, and quadriparesis, which ultimately led to the diagnosis of pSS and MG.