Predictive factors for pregnancy after controlled ovarian stimulation and intrauterine insemination: A retrospective analysis of 4146 cycles.

Background: The variability in indications and low rate of pregnancy compared to IVF have led many authors to dismiss IUI and offer IVF first-line instead.

Objectives: To determine what are the predictive factors for clinical pregnancy (CP) and live birth (LB) in intrauterine insemination (IUI) cycles following controlled ovarian stimulation (COS).

Methods: Retrospective unicentric study, between January 2009 and December 2016.

Female fertility preservation in cancer patients: an instrumental tool for the envisioning a postdisease life.

Aim: To verify whether fertility preservation (FP) improves the way women contemplate their life after the disease.

Materials & Methods: 285 cancer patients referred for FP counseling were prospectively studied. A standardized questionnaire was submitted to all participants.

[How to preserve female fertility before cancer treatments?].

Over the past decades, major advances in diagnosis and treatment have markedly improved the rates of cure for many young adults and children cancers. As a result, the field of fertility preservation (FP) has developed to overcome the adverse effects of cancer treatments on gonadal function. The strategy of FP will depend on patient's age, the puberty status, and the time frame before the initiation of gonadotoxic treatments.

In vitro maturation of oocytes: uncommon indications.

Retrieval of immature oocytes from unstimulated ovaries, followed by in vitro maturation (IVM) was initially proposed to avoid the risks and side effects of exogenous gonadotropin administration. Therefore, during the past decades, IVM was mainly offered to patients with polycystic ovary syndrome (PCOS) at high risk of ovarian hyperstimulation syndrome (OHSS). However, the development of fertility preservation has recently opened new perspectives in the field of IVM.

New trends in female fertility preservation: in vitro maturation of oocytes.

As antineoplastic treatments have become more successful, an increasing number of women with cancer survive to endure the long-term consequences of chemotherapy. One of the most important of these consequences in young females is premature ovarian failure and infertility. Owing to increasing survival rates, many of these young women are seeking methods to preserve their fertility.

Ovarian tissue and follicle transplantation as an option for fertility preservation.

Objective: To review and summarize data from the scientific literature on ovarian tissue and follicle transplantation as an option for fertility preservation.

Design: Review of pertinent literature.

Setting: University hospital.