Right prefrontal function and coping strategies in patients with remitted major depressive disorder.

Background: Patients with remitted major depressive disorder (rMDD) generally rely on maladaptive coping strategies for stressful situations. These maladaptive copings are associated with an elevated relapse risk of rMDD; however, their neural basis remains poorly understood.

Methods: We enrolled (1) 45 patients with rMDD (17-item Hamilton Depression Rating Scale [HRSD] total score ≤ 3) and (2) 56 healthy controls (HCs).

Aggressiveness is associated with excitement on the five-factor model of the positive and negative syndrome scale and prefrontal function in patients with stable schizophrenia.

Aggressiveness is a clinical concern in the stable phase of schizophrenia, as well as in the acute phase. The factors that affect aggressiveness during the stable phase remain unclear. This study investigated factors associated with aggressiveness in patients with stable schizophrenia.