Publications by authors named "Sohrab Salimi"

Background: The pain experienced following supratentorial brain surgery is usually defined as moderate to severe. Therefore, pain-management approaches, including narcotics, are an integral part of treatment regimens that cause respiratory complications or seizures, and reducing this pain level and increasing patient satisfaction is vital.

Methods: This randomized, double-blind clinical trial study to evaluate the pain level and satisfaction in patients undergoing surgery for supratentorial brain neoplasms was performed on two groups with a sample size of 50 patients.

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Purpose: Spine surgeries have experienced exponential growth over the past 2 decades. These surgeries are often accompanied by long and severe perioperative pain, presenting a significant management challenge. This study aims to assess and compare the efficacy of two techniques for postoperative pain (POP) management in lumbar spine surgeries: ultrasound-guided erector spinae plane block (ESPB) and intraoperative freehand ESPB.

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Background: To prove the position of aripiprazole as a preventive and safe agent in delirium in patients admitted to the intensive care unit (ICU), it is necessary to conduct randomized controlled clinical trials with appropriate design.

Materials And Methods: In this study, 80 patients were randomly divided into two groups of 40. Group A received placebo mart for one week, and group B received 15 mg aripiprazole daily (dissolved in 10 cc) daily.

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Background: Nonfunctioning pituitary adenomas (NFPAs) are the most common pituitary tumors and although they do not secrete hormones, they can have systemic effects. These tumors affect the function of other organs in the body by exerting pressure on the pituitary gland. There are differences between biomarkers NFPAs compared to healthy people.

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Background: Controversy remains about the positive role of music during general anesthesia and postoperative recovery. We, therefore, tested the hypothesis that intraoperative exposure to classical music reduces the propofol necessary to maintain the bispectral index (BIS) close to 50 during vitrectomy surgery.

Materials And Methods: This double-blind clinical study is evaluating 50 patients undergoing vitrectomy surgery under general anesthesia.

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Article Synopsis
  • The study investigates the effectiveness of premedication with oral tizanidine on alleviating shoulder pain after laparoscopic cholecystectomy, a common postoperative complication.
  • It involved 75 adult patients who were randomly divided into three groups: one receiving tizanidine, another receiving pregabalin, and a control group receiving a placebo, with pain levels monitored for 24 hours post-surgery.
  • Results showed that both tizanidine and pregabalin significantly reduced pain intensity and the need for additional pain relief compared to the control group, with no notable side effects.
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is an autoimmune disorder presented by ascending paralysis and areflexia. The condition has been reported after many infections, but Guillain-Barré syndrome after spine surgery is rare. We, herein, present a case of Guillain-Barré syndrome after multiple spine surgeries for degenerative lumbar scoliosis.

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Introduction: Posterior cerebral artery (PCA) aneurysms are a rare group of intracranial aneurysms. Pediatric aneurysms account for approximately 4% of all aneurysms and are commonly associated with an underlying predisposing disorder, such as trauma. In contrast to traumatic aneurysms, spontaneous dissecting cases are pointed out as a rare cause of pediatric aneurysms.

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Low pressure laparoscopic cholecystectomy has been advocated due to reduction in postoperative pain, ventilation problems, hemodynamic complications, and potential for reduction in surgical events. No reported data have been found focusing on the effects of low-pressure laparoscopic cholecystectomy on intracranial pressure (ICP). The aim of this study was to investigate the effect of low-pressure laparoscopic cholecystectomy on intracranial pressure measured by optic nerve sheath diameter (ONSD) in Imam Hossein Medical Center, Tehran, Iran.

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Article Synopsis
  • Sexual violence has significant long-term physical and psychological effects on victims, with a notable portion of rectal foreign body (RFB) cases resulting from sexual assault and patients often delaying reporting their injuries.
  • The case presentations involved three male patients, averaging 41 years old, who sought help about two days post-assault due to foreign objects resulting from violence; these included items like bottles and water pipes.
  • Treatment of these cases must prioritize not only the physical removal of the foreign bodies, using methods ranging from anal procedures to surgical intervention, but also address the psychological trauma to support the patient's overall recovery.
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Background: Severe varus deformity of the knee poses a technical challenge in balancing the flexion-extension gaps. The use of a varus-valgus constrained prosthesis is a solution to achieve coronal plane stability. The results of constrained condylar knee (CCK) implants in primary total knee arthroplasty are not well known.

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Background: The present study aims to evaluate the diagnostic exactitude of the intraoperative Chertsey test in tibiofibular syndesmotic injuries in patients with malleolar fractures, in comparison with a computed tomography (CT) scan.

Materials And Methods: In this study, patients with malleolar fractures operated between 2018 and 2020 were examined. Thirty-nine patients were enrolled in the study.

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Article Synopsis
  • - This study tested whether using intra-wound vancomycin reduces post-surgery infections by comparing two groups: one that received the drug and another that did not.
  • - A total of 375 patients were analyzed for surgical site infections (SSI) after three months, with similar infection rates in both treatment (12 cases) and control groups (11 cases), indicating no significant benefit from vancomycin.
  • - The findings suggest that intra-wound vancomycin does not lower SSI rates and may even lead to a higher occurrence of gram-negative bacterial infections.
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Purpose: Primary pediatric tumors are the most common solid tumors in children. There are limited reports on the management and outcome of these tumors in the developing countries. In recent years, advances have been done in the diagnosis, treatment, and outcome of these tumors.

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In this retrospective multicenter case series study, the predictive value of initial findings of confirm COVID-19 cases in determining outcome of the disease was assessed. Patients were divided into two groups based on the outcome: low risk (hospitalization in the infectious disease ward and discharge) and high risk (hospitalization in ICU or death). A total of 164 patients with positive PCR-RT were enrolled in this study.

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Background: Designing information systems will increase the efficiency and effectiveness of the system according to the information needs of the stakeholders. The present study examined the effective features of designing the information system of medicinal plants from the perspective of its users as a prerequisite for the design of this system.

Materials And Methods: This applied research was carried out using survey method and a researcher-made questionnaire.

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Article Synopsis
  • Psoriasis is a chronic skin condition driven by T-cell activity, with complex causes that researchers are actively exploring to improve treatment options.
  • Recent advancements have led to biologic drugs targeting specific immune pathways, including new IL-23p19 inhibitors that offer a safer approach to managing psoriasis.
  • This review will focus on how IL-23 and Th17 cell signaling contribute to psoriasis and will summarize the clinical outcomes of using the IL-23p19 inhibitor mirikizumab in treating chronic plaque psoriasis.
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Objectives: Meningioma is the most common brain tumor in adults. Grade 1 meningiomas have excellent prognoses, but grades 2 and 3 usually have worse outcomes, higher recurrence rates, and higher mortality rates. Preoperative determination of tumor grade may be helpful in deciding the type of surgery and the rate of resection.

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Recently there is a surge in cosmetic and aesthetic surgery procedures. Several patient seeking various cosmetics procedures present to aesthetic surgery clinics and demanding procedures which are out of proportion. Several of these patients have under-recognized or untreated psychiatric disorders.

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Background: Melatonin has anxiolytic and potential analgesic effects. Several studies have indicated the sedative and anti-anxiety effects of melatonin when used as premedication before surgery. Hence, we assessed the efficacy of melatonin premedication in tourniquet-related pain and analgesia in patients receiving intravenous regional anesthesia (IVRA).

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Background: Ankle fracture-dislocation with a syndesmotic injury has been treated with syndesmotic screw fixation. There are little evidences about the safety and efficacy of syndesmotic screw removal on the syndesmotic malreduction. This study aimed to evaluate the effects of syndesmotic screw removal of distal attachment of the fibula and tibia bones on the syndesmotic reduction and also impact of syndesmotic screw removal on the final functional score of ankle joint.

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  • This study investigates the effectiveness of a combination of five sedatives (low-dose fentanyl, propofol, midazolam, ketamine, and lidocaine) compared to a regular combination of two drugs (propofol and fentanyl) for inducing deep sedation in emergency department patients.
  • A total of 125 patients, aged 15 to 60 with high pain scores, were randomly assigned to two groups and assessed for onset of action, recovery time, and side effects.
  • Results showed that 100% of patients in the five-drug group achieved deep sedation within 3 minutes, while only 56.5% in the two-drug group did; however, recovery time was slightly longer for the five-dr
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Background: Heat loss and core-to-peripheral redistribution of body heat occur in patients undergoing neuraxial anesthesia resulted to decrease of core temperature and early reach of shivering threshold. Because shivering has deleterious metabolic and cardiovascular effects, it should ideally be prevented by pharmacologic or other means. Tizanidine is an alpha-2 agonist.

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