Developing water, energy, and food sustainability performance indicators for agricultural systems.

Water use by the agricultural sector along with inefficient irrigation methods and climate change has led to the depletion and insecurity of water resources and consequent instability of the agricultural system. Defining benchmarks and comparing them is essential for sustainable system management performance. The sustainability performance of an agricultural system depends on various factors related to water, energy, and food.

Multivariate modeling of pan evaporation in monthly temporal resolution using a hybrid evolutionary data-driven method (case study: Urmia Lake and Gavkhouni basins).

Evaporation is an important meteorological variable that has a great impact on water resources. In the current research, climatology data, and seasonal coefficient have been used to estimate monthly pan evaporation (E) for 2005-2018 study years at four selected stations of the Urmia Lake basin with Dsa and six selected stations of Gavkhouni basin with Bsk climate categories, in Iran. Estimation of monthly E was performed using data-driven methods such as artificial neural networks (ANNs), adaptive neuro-fuzzy inference system (ANFIS), and gene expression programming (GEP) as well as wavelet-hybrids (WANN, WANFIS, and WGEP).

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia, which challenges the molecular analyses of bulk tumor samples. Here we FACS-purified epithelial cells from human PDAC and normal pancreas and derived their genome-wide transcriptome and DNA methylome landscapes. Clustering based on DNA methylation revealed two distinct PDAC groups displaying different methylation patterns at regions encoding repeat elements.

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.

Objective: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumour thought to arise from ductal cells via pancreatic intraepithelial neoplasia (PanIN) precursor lesions. Modelling of different genetic events in mice suggests both ductal and acinar cells can give rise to PDAC. However, the impact of cellular context alone on tumour development and phenotype is unknown.

The effects of triggers' modifying on adolescent self-efficacy with asthma: a randomized controlled clinical trial.

Introduction: The management of asthma during adolescence has specific challenges and is likely influenced, to some extent, by the patient's belief in their ability to affect change, their self-efficacy. Bolstering self-efficacy could potentially improve an adolescent's ability to self-manage their asthma. The aim of this study was to examine the effects of a triggers' educational-modifying intervention on self-efficacy among adolescents diagnosed with asthma living in Iran.

The Effect of Educational and Modifying Intervention on Asthma Control among Adolescents: a Randomized Clinical Trial.

Introduction: Controlling over allergens and environmental irritants is one of the essential elements of controlling asthma. Asthma control in adolescents is a challenge. The current study was performed with the goal of investigating the effect of an educational and modifying intervention about asthma triggers on asthma control among adolescents.