Publications by authors named "Soheila Habibi Ghahfarokhi"
Background: The number of erythromycin-resistant has significantly increased around the world. The present study aimed to determine the serotype distribution and molecular epidemiology of the erythromycin-resistant (ERSP) isolated from patients with invasive disease.
Methods: A total of 44 isolates were tested for susceptibility to several antimicrobial agents.
Article Synopsis
- - The study investigates the relationship between antimicrobial resistance and amino acid mutations in penicillin-binding proteins of Streptococcus pneumoniae, as well as characterizing penicillin-nonsusceptible isolates in Iran through molecular methods.
- - Out of 149 tested isolates, 53 were identified as penicillin-nonsusceptible, revealing significant percentages of resistance to other antibiotics like ceftriaxone and cefotaxime, along with various serotypes and genotypes.
- - To combat rising antimicrobial resistance, the research suggests that broader vaccination efforts, particularly using the 13-valent pneumococcal conjugate vaccine, could effectively lower the incidence of severe invasive pneumococcal diseases.
Introduction: Encapsulated strains cause high morbidity and mortality, mainly in countries with no pneumococcal conjugate vaccines (PCVs) immunization program. This study investigated the epidemiological changes of isolates including serotype distribution and antimicrobial susceptibility in Tehran, Iran.
Methods: A total of 80 samples were collected from patients admitted to Shariati hospital over two periods.