Effect of photobiomodulation therapy on TGF-β release from dentin, migration and viability of dental pulp stem cells in regenerative endodontics treatment: An ex vivo study.

Background And Aim: Regenerative endodontic procedures (REPs) are oriented by the principles of tissue engineering, incorporating dental pulp stem cells (DPSC), crucial growth factors like Transforming growth factor-β (TGF-β1), and scaffolds to facilitate the regeneration of dental pulp tissues. The present study aimed to investigate the effect of photobiomodulation (PBM) therapy, using an 808 nm diode laser on cellular modulation mechanisms in REPs.

Method And Material: A total of 108 human dentin discs obtained from intact single root teeth were randomly assigned into six groups (n = 8): 1.

Mandibular Second Premolar with Four Canals: A Case Report.

The mandibular second premolar can be considered one of the most challenging teeth to treat endodontically; due to the complexity of its root canal morphology and increased incidence of multiple canals. The knowledge of internal anatomy of root canals and their possible variations as well as use of magnification, operating microscope, radiographic examination and illumination, can increase the chances of finding additional canals and contribute to the success of endodontic treatment. The purpose of the current investigation is to report the successful endodontic treatment of a mandibular second premolar with 4 canals; all of them in one single root.

Diagnosis and Treatment of an Incomplete Crown-Root Fracture with Intentional Replantation: A Case Report.

Acute traumatic injuries to the maxillary incisors may lead to a crown-root fracture. If the fracture is left untreated, the fracture line will propagate and extend apically, resulting in microbial contamination of the attachment apparatus and subsequent bone loss. In cases with extensive periodontal involvement, extraction has been suggested.

Management of a Large Periapical Lesion Using Decompression: A Case Report with Three-year Follow-up.

Large radicular lesions should be treated initially by orthograde root canal therapy. When the signs and symptoms of the infection ( persistent purulent drainage) do not resolve after this treatment, then surgical approaches should be considered. In the cases of large radicular cysts, total enucleation of the cyst can endanger adjacent structures and teeth.

Effect of photobiomodulation on pain level during local anesthesia injection: a randomized clinical trial.

The aim of this study was to investigate the effect of photobiomodulation therapy (PBMT) as pre-treatment on pain level during injection in the anterior maxillary region. 56 Patients were randomly divided into 3 groups, Group 1:980 nm diode laser (n = 22) (experimental), Group 2:980 nm diode laser probe placed in vestibule without radiation (placebo) (n = 22), Group3: no pre-treatment before injection (n = 12) (control). Pain level during injection was evaluated by visual analog scale (VAS).

Effect of ultrasonic activation on the efficacy of antimicrobial photodynamic therapy: Evaluation of penetration depth of photosensitizer and elimination of Enterococcus faecalis biofilms.

Background: This study aimed to assess the effect of ultrasonic activation of photosensitizer on the efficacy of Antimicrobial Photodynamic Therapy (aPDT) against Enterococcus faecalis and penetration depth of photosensitizer.

Materials And Methods: In this ex vivo study, mature microbial biofilm of E. faecalis was formed in the root canals of 58 single-rooted single-canal mandibular incisors following their decoronation.