Publications by authors named "Sohan P Selkar"

Article Synopsis
  • Hypertension is a common issue during pregnancy, specifically characterized as Pregnancy Induced Hypertension (PIH), linked to changes in endothelial function and nitric oxide levels.
  • Research aimed to investigate the role of reactive nitrogen species in PIH, comparing 60 patients with PIH to 60 without.
  • The study found lower nitric oxide levels, higher S-nitrothiol levels, and decreased thiol levels in PIH patients, suggesting that nitrosative stress may play a key role in the development of PIH due to antioxidant depletion.
View Article and Find Full Text PDF

The ulceration associated with gout tophi is very difficult to treat because of impaired and halted local inflammatory response resulting from the gout treatment regimen. We report chronic nonhealing tophaceous gout with bursitis in an 80-year-old male, not responding to conventional treatment modality for months together. This nonhealing ulcer was treated successfully with local application of 3% citric acid ointment for 22 days.

View Article and Find Full Text PDF

Background And Objectives: Low Back Pain (LBP) results in significant level of disability, producing significant restriction on usual activity such as an inability to work. Nearly two third of the adults are affected by non-specific low back pain at some point in their lives. The purpose of the study was to determine the effect of core stabilization exercises in comparison with conventional exercises on pain, functional status in patients with non-specific LBP.

View Article and Find Full Text PDF

A prospective study was carried out to assess the role of citric acid as a sole antimicrobial agent in the management of lepromatous ulcers. Thirty-four known cases of lepromatous ulcers not responding to conventional antibiotic therapies for long duration were investigated for culture and susceptibility studies. Staphylococcus aureus (25·00%) and Klebsiella spp.

View Article and Find Full Text PDF

Necrotizing fasciitis is a destructive invasive infection of skin, subcutaneous tissue and deep fascia, with relative sparing of muscle. It is a life-threatening condition. Here we report two cases of necrotizing fasciitis, which were not responding to conventional antibiotic therapy and local wound care after aggressive debridement.

View Article and Find Full Text PDF

Objective: The aim of the present study was to develop a simple and effective treatment modality using citric acid as a sole antimicrobial agent to control infections in burns patients not responding to conventional treatment.

Methods: Forty-six cases with 5-60% superficial to deep burns in a study group and 20 cases with 10-70% superficial to deep burns in a control group were investigated for culture and susceptibility. The isolates in study group were further tested for susceptibility to citric acid.

View Article and Find Full Text PDF

Diabetic foot infections are the major cause of morbidity. Infection is the common sequel of diabetic foot ulceration that leads to delayed wound healing. These infections are difficult to control.

View Article and Find Full Text PDF