Publications by authors named "Sohaira Tahir"
Chronic traumatic encephalopathy (CTE) is a progressive and fatal neurological disorder linked to repeated traumatic brain injuries (TBIs), including concussions and blows to the head. This condition is characterized by the accumulation of abnormally structured hyperphosphorylated tau proteins (p-tau), forming neurofibrillary tangles, astrocytic tangles, and neurites in the brain. CTE is often diagnosed post-mortem, making it challenging to diagnose and predict its progression in living individuals.
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- Neurosarcoidosis is a rare form of sarcoidosis that affects the nervous system, leading to symptoms like seizures, cognitive issues, and cranial nerve problems, which complicate diagnosis and management due to their variability.
- Diagnosing the condition requires a mix of clinical assessments, advanced imaging (like high-resolution MRI and PET scans), and lab tests, but it can be mistaken for conditions like multiple sclerosis.
- Treatment often starts with corticosteroids and may include immunosuppressants or biologic therapies for more severe cases, with ongoing research aimed at better understanding the disease and improving therapies through biomarkers and innovative technologies.