Publications by authors named "Soha Mohammadi"
Article Synopsis
- Severe combined immunodeficiencies (SCIDs) are genetic disorders leading to malfunctioning immune systems due to issues with T and B cells, with many cases linked to RAG mutations.
- This report details two siblings who both had SCID caused by a new mutation in the RAG2 gene, affecting their immune responses and leading to serious health complications.
- The findings emphasize the importance of ongoing research to better understand the mutation's effects, as well as improving communication among healthcare professionals to enhance patient care.
Background: Lower lip squamous cell carcinoma is a significant subtype of head and neck cancer, constituting about 25-30% of cases. Traditional surgical methods, like primary closure, have limitations in managing large resections of lip tumors. Recent advancements in surgical techniques, particularly free flaps, have shown promising results in addressing these challenges.
View Article and Find Full Text PDFBackground: Epigenetic modifications, particularly histone acetylation-deacetylation and its related enzymes, such as sirtuin 1 (SIRT1) deacetylase, may have substantial roles in the pathogenesis of obesity and its associated health issues. This study aimed to evaluate global histone acetylation status and SIRT1 gene expression in children and adolescents with obesity and their association with metabolic and anthropometric parameters.
Methods: This study included 60 children and adolescents, 30 with obesity and 30 normal-weight.
Background: Programmed death ligand 1 (PD-L1) plays critical role in PD-1-dependent immunity suppress. Abnormal PD-L1 expression has shown to be directly related to poor prognosis and drug resistance in cancer patients. Hence, we aimed to evaluate PD-L1 expression in relapsing and remitting Hodgkin lymphoma (HL) as a prognostic factor.
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