Multi-Omics of Growth in Chicken Exudate Reveals Molecular Remodelling Associated with Altered Virulence and Survival Phenotypes.

is the leading cause of foodborne human gastroenteritis in the developed world. Infections are largely acquired from poultry produced for human consumption and poor food handling is thus a major risk factor. Chicken exudate (CE) is a liquid produced from defrosted commercial chicken products that facilitates growth.

Effectiveness of non-pharmacological interventions in improving sleep quality after cardiac surgery: A systematic review and meta-analysis.

Background: Sleep disturbance is highly prevalent among post-operative cardiac patients, with negative impacts on surgical recovery and rehabilitation. Post-operative pain and anxiety commonly seen in cardiac surgery patients are associated with poor sleep. Sleep medications commonly used are not ideal with prolonged usage, and non-pharmacological interventions can be good alternatives or complements.

Genomic Analysis of Lymphoma Risk in Bullmastiff Dogs.

Lymphoma is the most common haematological malignancy affecting dogs and has a high incidence in the Bullmastiff breed. The aim of this study was to identify risk loci predisposing this breed to the disease. The average age of lymphoma diagnosis in 55 cases was less than 6 years, similar to the median age of 64 cases from our clinical and pathology databases.

Prostate cancer genetic risk and associated aggressive disease in men of African ancestry.

African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common risk variants contributing to a multiethnic polygenic risk score, with rare variants focused on a panel of roughly 20 pathogenic genes. Based on this knowledge, we are unable to determine polygenic risk or differentiate prostate cancer status interrogating whole genome data for 113 Black South African men.

Lymphoma in Border Collies: Genome-Wide Association and Pedigree Analysis.

There has been considerable interest in studying cancer in dogs and its potential as a model system for humans. One area of research has been the search for genetic risk variants in canine lymphoma, which is amongst the most common canine cancers. Previous studies have focused on a limited number of breeds, but none have included Border Collies.

ANO7 African-ancestral genomic diversity and advanced prostate cancer.

Background: Prostate cancer (PCa) is a significant health burden for African men, with mortality rates more than double global averages. The prostate specific Anoctamin 7 (ANO7) gene linked with poor patient outcomes has recently been identified as the target for an African-specific protein-truncating PCa-risk allele.

Methods: Here we determined the role of ANO7 in a study of 889 men from southern Africa, leveraging exomic genotyping array PCa case-control data (n = 780, 17 ANO7 alleles) and deep sequenced whole genome data for germline and tumour ANO7 interrogation (n = 109), while providing clinicopathologically matched European-derived sequence data comparative analyses (n = 57).

Microstrip Sensor Based on Ring Resonator Coupled with Double Square Split Ring Resonator for Solid Material Permittivity Characterization.

This paper analyzes a microwave resonator sensor based on a square split-ring resonator operating at 5.122 GHz for permittivity characterization of a material under test (MUT). A single-ring square resonator edge (S-SRR) is coupled with several double-split square ring resonators to form the structure (D-SRR).

'But what if you miss something …?': factors that influence medical student consideration of cost in decision making.

Context: Cost-conscious care is critical for healthcare sustainability but evidence suggests that most doctors do not consider cost in their clinical decision making. A critical step in changing this is understanding the barriers to encouraging behaviours and attitudes related to cost-conscious care. We therefore conducted a qualitative study to address the research question: what factors influence consideration of cost in emergency medicine (ED) clinical decision making?

Methods: This was a qualitative focus group study using patient vignettes to explore attitudes towards cost-conscious clinical decision making.

Resonance Analysis and Gain Estimation Using CMA-Based Even Mode Combination Method for Flexible Wideband Antennas.

This work presents an efficient design and optimization method based on characteristic mode analysis (CMA) to predict the resonance and gain of wideband antennas made from flexible materials. Known as the even mode combination (EMC) method based on CMA, the forward gain is estimated based on the principle of summing the electric field magnitudes of the first even dominant modes of the antenna. To demonstrate its effectiveness, two compact, flexible planar monopole antennas designed on different materials and two different feeding methods are presented and analyzed.

Evaluating Germline Testing Panels in Southern African Males With Advanced Prostate Cancer.

Background: Germline testing for prostate cancer is on the increase, with clinical implications for risk assessment, treatment, and management. Regardless of family history, NCCN recommends germline testing for patients with metastatic, regional, very-high-risk localized, and high-risk localized prostate cancer. Although African ancestry is a significant risk factor for aggressive prostate cancer, due to a lack of available data no testing criteria have been established for ethnic minorities.

Direct oral anticoagulants and warfarin safety in rural patients with obesity.

Background: Direct oral anticoagulants (DOACs) are often used in patients with atrial fibrillation or flutter instead of warfarin and although supporting evidence is limited, available studies suggest this may be an acceptable route of care. Our study assessed the question: are DOACs as effective and safe as warfarin in patients with atrial fibrillation and class III obesity specifically in a rural population?

Methods: A retrospective analysis was conducted by examining the first 6-12 months of therapy with a DOAC (apixaban or rivaroxaban) or warfarin in patients with weight >120kg or class III obesity. Events of interest, thrombosis and bleeding, were documented for analysis.

Combined RIS and EBG Surfaces Inspired Meta-Wearable Textile MIMO Antenna Using Viscose-Wool Felt.

In this paper, we present a textile multiple-input−multiple-output (MIMO) antenna designed with a metamaterial inspired reactive impedance surface (RIS) and electromagnetic bandgap (EBG) using viscose-wool felt. Rectangular RIS was used as a reflector to improve the antenna gain and bandwidth to address well known crucial challenges—maintaining gain while reducing mutual coupling in MIMO antennas. The RIS unit cell was designed to achieve inductive impedance at the center frequency of 2.

Design of Quad-Band Bandpass Filter Using Dual-Mode SLRs and Coupled-Line for DCS/WLAN/WiMAX and 5G Applications.

A design of a microstrip quad-band BPF with flexibly controlled bandwidth is presented in this paper. Two dual-mode short-circuited SLRs with a common via-hole are proposed, which are utilized to obtain the first and second passband, while the third passband is generated by implementing the second-order half-wavelength coupled-line resonator. Another dual-mode open-circuited SLR can be operated at the fourth passband.

Oophorectomy for ovarian torsion - should this be abandoned?

Background: Management of ovarian torsion ranges from de-torsion to oophorectomy and is dependent on various factors. Oophorectomy can have significant implications for fertility and general health, thus requiring careful consideration.

Aims: We evaluate the management of ovarian torsion at a tertiary hospital over a ten-year period and identify the predictors of oophorectomy in ovarian torsion cases.

Design of a Compact Dual-Band Textile Antenna Based on Metasurface.

This paper presents a compact textile antenna design based on a metasurface for wearable applications. It operates in the 2.45 GHz and 5.

A Negative Index Nonagonal CSRR Metamaterial-Based Compact Flexible Planar Monopole Antenna for Ultrawideband Applications Using Viscose-Wool Felt.

In this paper, a compact textile ultrawideband (UWB) planar monopole antenna loaded with a metamaterial unit cell array (MTMUCA) structure with epsilon-negative (ENG) and near-zero refractive index (NZRI) properties is proposed. The proposed MTMUCA was constructed based on a combination of a rectangular- and a nonagonal-shaped unit cell. The size of the antenna was 0.

Bandwidth Optimization of a Textile PIFA with DGS Using Characteristic Mode Analysis.

This work presents the design and optimization of an antenna with defected ground structure (DGS) using characteristic mode analysis (CMA) to enhance bandwidth. This DGS is integrated with a rectangular patch with circular meandered rings (RPCMR) in a wearable format fully using textiles for wireless body area network (WBAN) application. For this integration process, both CMA and the method of moments (MoM) were applied using the same electromagnetic simulation software.

Electrically Tunable Left-Handed Textile Metamaterial for Microwave Applications.

An electrically tunable, textile-based metamaterial (MTM) is presented in this work. The proposed MTM unit cell consists of a decagonal-shaped split-ring resonator and a slotted ground plane integrated with RF varactor diodes. The characteristics of the proposed MTM were first studied independently using a single unit cell, prior to different array combinations consisting of 1 × 2, 2 × 1, and 2 × 2 unit cells.

Evaluation of genetic diversity and management of disease in Border Collie dogs.

Maintaining genetic diversity in dog breeds is an important consideration for the management of inherited diseases. We evaluated genetic diversity in Border Collies using molecular and genealogical methods, and examined changes to genetic diversity when carriers for Trapped Neutrophil Syndrome (TNS) and Neuronal Ceroid Lipofuscinosis (NCL) are removed from the genotyped population. Genotype data for 255 Border Collies and a pedigree database of 83,996 Border Collies were used for analysis.

Liquid-Based Reconfigurable Antenna Technology: Recent Developments, Challenges and Future.

Advances in reconfigurable liquid-based reconfigurable antennas are enabling new possibilities to fulfil the requirements of more advanced wireless communication systems. In this review, a comparative analysis of various state-of-the-art concepts and techniques for designing reconfigurable antennas using liquid is presented. First, the electrical properties of different liquids at room temperature commonly used in reconfigurable antennas are identified.

Meta-Wearable Antennas-A Review of Metamaterial Based Antennas in Wireless Body Area Networks.

Wireless Body Area Network (WBAN) has attracted more and more attention in many sectors of society. As a critical component in these systems, wearable antennas suffer from several serious challenges, e.g.

In vitro susceptibility of Mycobacterium abscessus complex and feasibility of standardizing treatment regimens.

Objectives: To determine the in vitro susceptibility of members of the Mycobacterium abscessus complex to routinely tested antibiotics and to an extended antibiotic panel.

Methods: Non-duplicate isolates for which susceptibility testing results were available were included in this study. Retrospective laboratory records were reviewed, including tigecycline susceptibility results, and testing was performed with additional drugs, including vancomycin, dalbavancin, telavancin, oritavancin, rifabutin, delafloxacin, eravacycline, clofazimine and bedaquiline using broth microdilution (Sensititre, Thermo Fisher).