Publications by authors named "Sogol Koolaji"

Background: This study presents estimates for type 2 diabetes mellitus (T2DM) burden and attributable risk factors in Iran from 1990-2019, using data from the 2019 Global Burden of Disease study.

Methods: This study reports prevalence, incidence, death, disability-adjusted life years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) of T2DM in Iran, by sex, age, and province, from 1990 to 2019. We also present the T2DM burden attributable to risk factors.

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Background: Primary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment.

Case Presentation: This paper presents the case of a 40-year-old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma.

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  • - The study compares the quality of care and healthcare inequities for cervical and ovarian cancers using the Quality of Care Index (QCI), revealing disparities in treatment performance across different regions and income levels worldwide.
  • - Data from 1990 to 2019 indicates that while cervical cancer incidence has decreased, ovarian cancer cases have risen, yet mortality rates for both have reduced, with QCI values increasing for both types of cancer over this period.
  • - The results highlight that higher-income countries generally provide better care, but age and socio-demographic factors contribute to inequities in care quality, stressing the urgent need for targeted improvements and further research to address these disparities.
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  • The study aims to analyze trends in metabolic risk factors (MRFs) among the elderly (60 years and older) using data from 1990 to 2016.
  • The results show significant increases in the prevalence of overweight/obesity, diabetes, and hypertension in the elderly population, with women showing a higher overall prevalence compared to men.
  • The findings indicate a need for targeted public health initiatives to address the rising rates of non-communicable diseases and improve preventive care for this demographic.
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  • - This study investigated the prevalence of hypertension (HTN) and pre-hypertension (PHTN) in 429 districts across Iran, finding significant inequalities in these health issues among different regions.
  • - Data from over 27,000 participants revealed that crude prevalence rates for HTN ranged from 11.5% to 42.2%, while PHTN rates ranged from 19.9% to 56.1%, with varying levels of awareness and treatment coverage.
  • - The findings indicate that central regions and females generally had better health outcomes, suggesting that policymakers should focus on addressing these disparities in resources and hypertension management.
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Introduction: Serum uric acid has been suggested as an independent marker of oxidative metabolism in chronic obstructive pulmonary disease (COPD), a disease with significant social, health, and economic burden. Therefore, we aimed to investigate the role of this factor in COPD exacerbation.

Methods: We investigated 20- to 70-year-old patients who were admitted due to COPD exacerbation (acute phase) or presented to the pulmonary clinic for follow-up (non-acute phase).

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  • - The study investigated diabetes mellitus (DM) and prediabetes in Iran using data from the 2021 Iran STEPS Survey, focusing on awareness, treatment coverage, and adherence to World Health Organization targets.
  • - Findings revealed that 14.2% of participants had DM and 24.8% had prediabetes, with treatment coverage at 65% but only 28% achieving good glycemic control (HbA1C < 7%).
  • - While diagnosis and statin use were close to global targets, overall glycemic control and blood pressure management were significantly below the desired levels, highlighting insufficient diabetes care in the population.
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Background: Sustainable Development Goal 3.2 (SDG 3.2) is to reduce Under-5 and neonatal mortality rates (U5MR and NMR), two major health systems' performance indicators, globally by 2030.

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  • This study analyzes the burden of ischemic heart disease (IHD) in Iran from 1990 to 2019 to guide healthcare policy development.
  • Findings revealed significant decreases in age-standardized death rates (42.7%) and disability-adjusted life years (DALYs) (47.7%), while incidence rates fell more slowly by only 7.7%.
  • The main risk factors contributing to deaths and DALYs were high blood pressure and LDL cholesterol, stressing the need for improved prevention strategies and management of rising health risks like high fasting glucose and body mass index (BMI).
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Background: Cancer is a major public health problem and comorbidity associated with COVID-19 infection. According to previous studies, a higher mortality rate of COVID-19 in cancer patients has been reported.

Aims: This study was undertaken to determine associated risk factors and epidemiological characteristics of hospitalized COVID-19 patients with cancer using a nationwide COVID-19 hospital data registry in Iran for the first time.

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Introduction: Epicardial pacemakers are known as an alternative for endocardial pacemakers in some cases such as heart block, and complex congenital heart diseases. Considering recent advances and improvement of epicardial lead subtypes, it is essential to investigate the long-term function of them. In this study, we aimed to assess the sensing and pacing characteristics, and survival of bipolar steroid-eluting and unipolar nonsteroid-eluting epicardial pacemakers.

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Background: Alcohol is a leading risk factor for over 200 conditions and an important contributor to socioeconomic health inequalities. However, little is known about the associations between individuals' socioeconomic circumstances and alcohol consumption, especially heavy episodic drinking (HED; ≥5 drinks on one occasion) in low-income or middle-income countries. We investigated the association between individual and household level socioeconomic status, and alcohol drinking habits in these settings.

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Background: While several studies investigated the epidemiology and burden of stroke in the North Africa and Middle East region, no study has comprehensively evaluated the age-standardized attributable burden to all stroke subtypes and their risk factors yet.

Objective: The aim of the present study is to explore the regional distribution of the burden of stroke, including ischemic stroke, subarachnoid hemorrhage, and intracerebral hemorrhage, and the attributable burden to its risk factors in 2019 among the 21 countries of North Africa and Middle East super-region.

Methods: The data of the Global Burden of Disease Study (GBD) 2019 on stroke incidence, prevalence, death, disability-adjusted life years (DALYs), years of life lost (YLLs), years lived with disability (YLDs) rates, and attributed deaths, DALYs, YLLs, and YLDs to stroke risk factors were used for the present study.

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Background: Data on the burden of stroke and changing trends at national and subnational levels are necessary for policymakers to allocate recourses appropriately. This study presents estimates of the stroke burden from 1990 to 2019 using the results of the Global Burden of Disease (GBD) 2019 study.

Methods: For the GBD 2019, verbal autopsy and vital registration data were used to estimate stroke mortality.

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  • The study analyzes the burden and quality of care for liver cancer from 1990 to 2019, focusing on various causes like hepatitis B and C, alcohol use, and nonalcoholic steatohepatitis across different countries and demographic groups.
  • Findings revealed a global decrease in liver cancer incidence, disability-adjusted life years (DALYs), and death rates, alongside a 68.5% increase in the Quality of Care Index (QCI) indicating improved care standards.
  • Despite these improvements, significant disparities persist between high and low Sociodemographic Index (SDI) countries, emphasizing the need to address healthcare inequities and improve access.
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Introduction: COVID-19 clinical course, effective therapeutic regimen, and poor prognosis risk factors in pediatric cases are still under investigation and no approved vaccinehas been introduced for them.

Methods: This cross-sectional study evaluated different aspect of COVID-19 infection in hospitalized COVID-19 positive children (≺18 years oldwith laboratory confirmed COVID-19 infection, using the national COVID-19 registry for all admitted COVID-19 positive cases from February 19 until November 13,2020, in Iran.

Results: We evaluated 6610 hospitalized children.

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Purpose: The novel coronavirus disease 2019 (COVID-19) has imposed a great global burden on public health. As one of the most affected countries, Iran has tackled emerging challenges in the path to overcoming the epidemic, with three peaks of the disease propagation as of February 19, 2020. To flatten the curve of the COVID-19 pandemic, most countries have implemented bundles of intrusive, sometimes extremely stringent non-pharmaceutical interventions (NPIs).

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Background: Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dose intravenous vitamin C (HDIVC) to the regimens for patients with severe COVID-19 disease.

Methods: An open-label, randomized, and controlled trial was conducted on patients with severe COVID-19 infection.

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Anti-JC virus (JCV) antibody index is the predictive factor of progressive multifocal leukoencephalopathy (PML) for multiple sclerosis (MS) patients treating with natalizumab. The aim of this study is to evaluate the prevalence of anti-JCV antibody positivity and index among Iranian patients who are the candidate for natalizumab and its correlation with their demographic data and previous therapies. A cross-sectional design was assessed for receiving anti-JCV antibody test results between January 2014 and December 2016.

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