Modulation of Cerebellar Nuclear Activity by Transcranial AC Stimulation in Awake Rats.

Transcranial alternating current stimulation of the cerebellum (ctACS) is an emerging neuromodulation technique that can potentially be leveraged to treat neurological disorders and improve learning in healthy individuals. Yet, the effects of ctACS on the neuronal circuits of the cerebellum is elusive. We implanted carbon fiber bundle electrodes in the interpositus nucleus of the cerebellum and an array electrode on the posterior surface of the skull for stimulation in chronic rats.

Simulation of a Real-Time Brain Computer Interface for Detecting a Self-Paced Hitting Task.

Objectives: An invasive brain-computer interface (BCI) is a promising neurorehabilitation device for severely disabled patients. Although some systems have been shown to work well in restricted laboratory settings, their utility must be tested in less controlled, real-time environments. Our objective was to investigate whether a specific motor task could be reliably detected from multiunit intracortical signals from freely moving animals in a simulated, real-time setting.

Identification of a self-paced hitting task in freely moving rats based on adaptive spike detection from multi-unit M1 cortical signals.

Invasive brain-computer interfaces (BCIs) may prove to be a useful rehabilitation tool for severely disabled patients. Although some systems have shown to work well in restricted laboratory settings, their usefulness must be tested in less controlled environments. Our objective was to investigate if a specific motor task could reliably be detected from multi-unit intra-cortical signals from freely moving animals.