Publications by authors named "Sofie Pollenus"
Front Pharmacol
September 2023
Article Synopsis
- Surgical resection is crucial for treating various cancers, aiming for the complete removal of tumors and preventing relapse, which can negatively affect survival and quality of life.
- Fluorescence imaging enhances surgical outcomes by allowing surgeons to visualize malignant tissues through the use of fluorescent contrast agents, particularly utilizing Nanobodies (Nbs) that target specific tumor markers like the epidermal growth factor receptor (EGFR).
- A preliminary study in healthy dogs demonstrated that the fluorescently labeled anti-EGFR Nb 7D12-s775z was well tolerated without adverse effects, with encouraging imaging results suggesting rapid clearance, supporting further investigations in cancer treatments.
