Publications by authors named "Sofia Trompouki"
Background: Active vitamin D is an effective treatment for secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD) patients often complicated by hypercalcaemia and hyperphosphataemia. Treatment with paricalcitol, a selective vitamin D receptor activator, has shown benefits by adequately reducing parathyroid hormone (PTH) levels with minimal changes in serum calcium (Ca) and phosphorus (P). The purpose of this study is to present data on the use of oral paricalcitol in real-life clinical practice in patients with CKD stage 3-4 and SHPT.
View Article and Find Full Text PDFArticle Synopsis
- This study evaluated the effectiveness of two catheter-lock solutions, gentamicin/heparin and taurolidine/citrate, in preventing catheter-related bacteremia (CRB) in hemodialysis patients using uncuffed catheters (UCs).
- In a trial involving 119 patients and comparing with a historical control group, both solutions significantly reduced CRB episodes and improved catheter survival compared to heparin.
- The results showed no significant differences in thrombosis rates, indicating both solutions are effective for up to three months, making them better options than heparin for preventing CRB.
Sevelamer hydrochloride (SH) has been reported to aggravate metabolic acidosis and hyperkalemia. This study was performed to evaluate acid-base status and serum potassium changes after replacing SH with lanthanum carbonate (LC) in hemodialysis patients. SH was prescribed for 24 weeks in 14 stable hemodialysis patients and replaced by LC in a similar treatment schedule.
View Article and Find Full Text PDFA case of immunoglobulin A nephropathy (IgAN) complicating a 10-year history of biopsy-proven Crohn's disease in a 31-year-old man is described. The patient presented with mild proteinuria and impaired renal function in the setting of an exacerbation of Crohn's disease. Renal biopsy showed IgAN.
View Article and Find Full Text PDF