Publications by authors named "Sofia Triantafyllou"

Article Synopsis
  • Despite previous trials, it's still unclear how to effectively resuscitate patients with septic shock, prompting a deeper look into individual differences in treatment responses.
  • The study utilized machine learning to predict individual patient risk differences and evaluate how their characteristics affected treatment effectiveness across two large cohorts.
  • Results indicated significant variability in treatment responses; patients predicted to have the highest risks improved with early goal-directed therapy (EGDT), while those at lower risk potentially faced harm from the same treatment.
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A highly accurate but overconfident model is ill-suited for deployment in critical applications such as healthcare and autonomous driving. The classification outcome should reflect a high uncertainty on ambiguous in-distribution samples that lie close to the decision boundary. The model should also refrain from making overconfident decisions on samples that lie far outside its training distribution, far-out-of-distribution (far-OOD), or on unseen samples from novel classes that lie near its training distribution (near-OOD).

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Background: Very Brief Advice on smoking (VBA) is an evidence-based intervention designed to increase quit attempts among patients who smoke. VBA has been widely disseminated in general practice settings in the United Kingdom, however its transferability to Southern European settings is not well established. This study sought to document the perspectives of Greek general practice patients in terms of the acceptability and satisfaction with receiving VBA from their general practitioner (GP) and its influence on patients' motivation to make a quit attempt.

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