Exploring a Patient-Centered Methodology to Identify Suitable Proxy Conditions as a Source for Utility Data, Using Alopecia Areata as a Case Example.

Objectives: In the absence of EQ-5D utility data, the National Institute for Health and Care Excellence recommends sourcing utility values from a proxy health condition, provided that data indicate that the health-related quality of life (HRQoL) impact of the conditions is similar. Given that there is no standard practice for identifying proxy conditions, this study presents a patient-centered approach for selecting a proxy condition, using alopecia areata (AA) as an example.

Methods: A structured electronic search was conducted to identify conceptual models for conditions similar to AA with overlapping HRQoL domains.