Publications by authors named "Sofia Rubi"
Background: Opioid-related overdose is a leading cause of death for criminal legal-involved individuals and, although naloxone distribution and medications for opioid use disorder (MOUD) are effective means for reducing post-release overdose death risk, jail-based availability is limited. This case report describes the challenges faced by three Ohio communities as they implemented evidence-based practices (EBPs) in jails to combat post-release opioid overdose deaths.
Method: We present case examples of how barriers were overcome to implement jail-based EBPs in three Ohio communities (two urban and one rural) as part of the HEALing Communities Study (UM1DA049417; ClinicalTrials.
Article Synopsis
- This study explored insomnia rates and treatment interest among veterans from various racial/ethnic backgrounds, finding that 68% screened positive for insomnia, with the highest rates among Asian (90%) and Hispanic/Latine (79%) participants.
- Racial discrimination and PTSD symptoms were linked to more severe insomnia, while having a romantic partner appeared to offer some protective benefits.
- Interestingly, despite high insomnia rates, Asian and Hispanic/Latine veterans showed lower interest in sleep treatment, suggesting a complex relationship between race, mental health, and treatment-seeking behavior.
Prevalence and correlates of alcohol-induced blackout in a diverse sample of veterans.
Alcohol Clin Exp Res (Hoboken)
February 2023
Article Synopsis
- Alcohol-induced blackouts are common among veterans, with 53% experiencing them in the past year, especially among those who drink hazardously (68%).
- Racial discrimination is a major predictor of these blackouts, while drinking quantity and drug use showed significance only in earlier stages of analysis.
- Blackouts are linked to higher rates of depression symptoms, but not PTSD, suggesting that racial discrimination impacts mental health more significantly than immediate alcohol-related issues like blackouts.
Circadian genes in the medial accumbal shell (mNAcSh) region regulate binge alcohol consumption. Here, we investigated if antisense-induced knockdown of major circadian genes (Per1, Per2, and NPAS2) in the mNAcSh of mice exposed to intermittent access two-bottle choice (IA2BC) paradigm modulates the expression of histone deacetylase-2 (HDAC-2) and CREB-binding protein (CBP), key epigenetic modifiers associated with withdrawal-associated behaviors such as anxiety. Adult male C57BL/6J mice (N = 28), surgically implanted with bilateral guide cannulas above the mNAcSh, were chronically (4 weeks) exposed to alcohol (20% v/v) or saccharin (0.
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