Safety assessment of natural materials for food contact in high temperature applications: Migration studies with solid simulant (Tenax®).

The concern of conventional plastics for food contact has opened the use of natural vegetal materials which can be used even at high temperature. However, their safety in use has to be carefully evaluated. This study shows the migration tests of volatile compounds to Tenax® at 175 °C for 1 h.

Patched-Related Is Required for Proper Development of Embryonic Nervous System.

(), classified primarily as a neuroectodermal gene, encodes a protein with predicted topology and domain organization closely related to those of Patched (Ptc), the canonical receptor of the Hedgehog (Hh) pathway. To investigate the physiological function of Ptr in the developing nervous system, null mutant embryos were immunolabeled and imaged under confocal microscopy. These embryos displayed severe alterations in the morphology of the primary axonal tracts, reduced number, and altered distribution of the Repo-positive glia as well as peripheral nervous system defects.