Publications by authors named "Sofia M Tarchi"

Pursuing medical careers like radiology is challenging even for those with high levels of commitment, discipline, and resilience. Many rely on the guidance and support from mentors whose experiences serve as the roadmap for new generations. Unfortunately, finding a mentor can be difficult in certain parts of the world or when physicians decide to live and practice medicine outside their country of origin.

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  • Fibrosis is the abnormal buildup of connective tissue due to improper healing from injuries like lack of oxygen, infections, or trauma, affecting any organ and leading to dysfunction and failure.
  • It also plays a significant role in cancer development, making early diagnosis and monitoring vital for improving patient outcomes.
  • This paper specifically examines fibrosis in the genito-urinary system, highlighting current imaging technologies for detection and suggesting possible future research directions.
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Article Synopsis
  • Fibrosis is an abnormal buildup of connective tissue due to prolonged injuries like low oxygen, infections, or physical damage, which can lead to organ dysfunction and failure.
  • It is also linked to cancer development and progression, making early diagnosis and monitoring crucial for treatment and improving patient outcomes.
  • The text highlights the need for better understanding and application of advanced imaging techniques to detect fibrosis in abdominal organs, discussing both current technologies and future developments for early diagnosis.
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Article Synopsis
  • - Injury from factors like low oxygen, infections, or physical damage can disrupt normal tissue repair, leading to fibrosis, which affects organ function and can cause organ failure.
  • - Fibrosis plays a significant role in cancer development and progression, making early diagnosis and ongoing monitoring crucial for managing diseases and improving patients' quality of life.
  • - This work aims to review current imaging technologies used to detect fibrosis in thoracic organs and discuss future advancements in these imaging methods.
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Over the last five decades, breast density has been associated with increased risk of developing breast cancer. Mammographically dense breasts are considered those belonging to the heterogeneously dense breasts, and extremely dense breasts subgroups according to the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS). There is a statistically significant correlation between the increased mammographic density and the presence of more glandular tissue alone.

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  • - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, with genetic factors influencing disease severity and associated issues like blood clotting problems.
  • - A study examined genetic variants in hemostatic genes among 332 severe COVID-19 patients and 1,668 controls, identifying several genes linked to worse outcomes.
  • - Findings helped create a polygenic risk score to differentiate between severe cases and controls, with further analysis confirming the role of specific genetic variants in increasing the risk of severe COVID-19.
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