[Continuity of care between care levels: experiences of users in a municipal health network].

This study analyzes the experiences of users on the continuity of clinical management between care levels. This is a cross-sectional quantitative study that uses data from a survey conducted with 407 users of a public health network in Recife, Pernambuco State, Brazil, in 2017 and 2018. The experiences on the continuity of clinical management were explored from two dimensions: coherence of care and accessibility between levels of care.

Anti-Inflammatory Effect of Topiramate in a Chronic Model of TNBS-Induced Colitis.

Inflammatory bowel disease (IBD) is characterized by a chronic and relapsing inflammatory response in the gastrointestinal tract, resulting in severe symptoms such as abdominal pain, vomiting, diarrhea, bloody stools, and weight loss. Currently, there is no cure, and the pharmacological treatment includes drugs that induce and keep the patient in remission, not reversing the underlying pathogenic mechanism. These therapies, in the long term, may cause various side effects and complications, which has increased the need to investigate new, more effective, and safer pharmacological approaches.

Combining time-driven activity-based costing and lean methodology: an initial study of single-level lumbar fusion surgery to assess value-based healthcare in patients undergoing spine surgery.

Objective: Measuring costs across entire episodes of care, time-driven activity-based costing (TDABC) has recently been described as a novel cost accounting arm of value-based care organizations. Lean methodology is a system used to understand pathways of care at a granular level, allowing for standardization. The current work presents an attempt at combining the 2 methodologies to detect meaningful variation in a patient's care following single-level spine fusion.

[Coordination of clinical management between levels: the views of physicians in primary and specialized care in Recife, Pernambuco State, Brazil].

This study analyzed the views of physicians towards coordination of clinical management between different levels of care. This was a cross-sectional quantitative study using data from a survey of 182 physicians in primary healthcare (PHC) and specialized care in Recife, Pernambuco State, Brazil, in 2017. The results revealed significant differences in the physicians' experience.

[Participatory modeling of educational activities in the Healthcare Planning strategy: backing for assessment of effectiveness].

The Healthcare Planning strategy is a powerful device for reorganization of work processes in healthcare networks and has been implemented by the Brazilian National Council of State Health Secretaries since 2013 in 25 health regions in 11 states, offering a set of educational activities for healthcare workers in the Brazilian Unified National Health System. This study aims to describe the process of participatory and consensual modeling of educational activities to back the assessment of the strategy's effectiveness. Development of the modeling used consultation with 18 key informants, selected intentionally according to their proximity to the educational activities' planning and execution.

Introduced Species, Disease Ecology, and Biodiversity-Disease Relationships.

Species introductions are a dominant component of biodiversity change but are not explicitly included in most discussions of biodiversity-disease relationships. This is a major oversight given the multitude of effects that introduced species have on both parasitism and native hosts. Drawing on both animal and plant systems, we review the competing mechanistic pathways by which biological introductions influence parasite diversity and prevalence.