Publications by authors named "Sofia Gomez"

Objective: Lipoprotein (a) [Lp(a)] is a causal, genetically-inherited risk amplifier for atherosclerotic cardiovascular disease (ASCVD). Practice guidelines increasingly recommend broad Lp(a) screening among various populations to optimize preventive care. Corresponding changes in testing rates and population-level detection of elevated Lp(a) in recent years has not been well described.

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Background: Large-scale data on incidental premature ventricular contraction (PVC) prevalence and morphologies have been lacking, leaving many providers without guidance on further cardiac testing for patients with incidental PVCs on ECG. Athletes offer an intriguing cohort to understand the clinical significance, prevalence, and common morphologies of incidental PVCs because they often undergo ECG screening during preparticipation exams.

Methods: Digital ECGs were obtained from 10 728 screened athletes aged 14 to 35 years during mass screenings in schools and professional sports teams between 2014 and 2021.

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Atherosclerotic cardiovascular (CV) disease (ASCVD) prevention encompasses interventions across the lifecourse: from primordial to primary and secondary prevention. Primordial prevention begins in childhood and involves the promotion of ideal CV health (CVH) via optimizing physical activity, body mass index, blood glucose levels, total cholesterol levels, blood pressure, and sleep while minimizing tobacco use. Primary and secondary prevention of ASCVD thereafter centers around mitigating ASCVD risk factors via medical therapy and lifestyle interventions.

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Recently, the manufacturing of porous polydimethylsiloxane (PDMS) with engineered porosity has gained considerable interest due to its tunable material properties and diverse applications. An innovative approach to control the porosity of PDMS is to use transient liquid phase water to improve its mechanical properties, which has been explored in this work. Adjusting the ratios of deionized water to the PDMS precursor during blending and subsequent curing processes allows for controlled porosity, yielding water emulsion foam with tailored properties.

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Article Synopsis
  • - The study investigated the prevalence of frequent premature ventricular contractions (PVCs) and nonsustained ventricular tachycardia (NSVT) in community-based women who are likely to have electrocardiogram (ECG) screening, focusing on postmenopausal participants at high risk for atrial fibrillation (AF).
  • - Among 1,067 women screened, 4.3% had frequent PVCs and 1.1% had episodes of NSVT, with both conditions showing a correlation to higher risk scores for having AF.
  • - Findings suggest that frequent PVCs are relatively common in this group, indicating that ongoing AF screening strategies should consider the prevalence of these incidental ventricular arrhythmias for better clinical decision
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The integration of 3D printed sensors into hosting structures has become a growing area of research due to simplified assembly procedures, reduced system complexity, and lower fabrication cost. Embedding 3D printed sensors into structures or bonding the sensors on surfaces are the two techniques for the integration of sensors. This review extensively discusses the fabrication of sensors through different additive manufacturing techniques.

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Introduction: Experience in the use of diagnostic and/or therapy of endoscopic retrograde cholangiopancreatography (ERCP) in children is limited. This is due to the underdiagnosis of pancreaticobiliary disease in the pediatric population and specialist personnel in this procedure.

Objective: To determine the safety and success rate of ERCP in children at Hospital Fundación Santa Fe de Bogotá between January 2007 and June 2015.

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Article Synopsis
  • Tyrosine kinase inhibitors (TKIs), especially ibrutinib, are commonly used to treat blood cancers, but there are concerns about arrhythmias associated with these medications.
  • A study analyzed 193 patients on long-term cardiac monitoring, revealing that those on ibrutinib had a significantly higher occurrence of atrial fibrillation and non-sustained ventricular tachycardia compared to those on other TKIs or non-TKI treatments.
  • The findings suggest that 25% of ibrutinib patients had to pause their treatment due to arrhythmias, highlighting the need for careful heart monitoring in patients receiving this type of therapy.
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Surface-associated lifestyles dominate in the bacterial world. Large multicellular assemblies, called biofilms, are essential to the survival of bacteria in harsh environments and are closely linked to antibiotic resistance in pathogenic strains. Biofilms stem from the surface colonization of a wide variety of substrates encountered by bacteria, from living tissues to inert materials.

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Article Synopsis
  • * When prescribed, women are also less likely to receive high-intensity dosing of statins (41.4% for women vs. 49.8% for men), especially among younger patients and those with private insurance.
  • * The study utilized Natural Language Processing (NLP) to analyze clinical notes, revealing that women were less frequently documented as being discussed for statin prescriptions and more likely to have statin intolerance noted.
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This research presents a simple method to additively manufacture Cone 5 porcelain clay ceramics by using the direct ink-write (DIW) printing technique. DIW has allowed the application of extruding highly viscous ceramic materials with relatively high-quality and good mechanical properties, which additionally allows a freedom of design and the capability of manufacturing complex geometrical shapes. Clay particles were mixed with deionized (DI) water at different ratios, where the most suitable composition for 3D printing was observed at a 1:5 w/c ratio (16.

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Background: Inflammatory cytokines play a role in atrial fibrillation (AF). Interleukin (IL)-1β, which is targeted in the treatment of ischemic heart disease, has not been well-studied in relation to AF.

Methods: Postmenopausal women from the Women's Health Initiative were included.

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Article Synopsis
  • Tyrosine kinase inhibitors (TKIs) are commonly used for treating various cancers, but they may lead to serious cardiovascular issues, particularly ventricular arrhythmias (VAs), which are not well-studied compared to other heart conditions.
  • A review of five patient cases from 2019 to 2022 found that VAs occurred in individuals with different heart health backgrounds, and these issues improved after stopping TKI therapy, although some needed additional heart medications or devices.
  • The study emphasizes the importance of recognizing the risk of VAs from TKIs in cancer patients and suggests the need for better monitoring and treatment methods to manage these potential cardiovascular side effects.
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There is a growing body of literature focusing on the morphology, management, and outcomes of PVCs in athletes. This review summarizes this literature and establishes recommendations on management, treatment, and indications for specialist referral in this patient population. The sports medicine physician's responses and recommendation should be made in conjunction with the athletes wishes.

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Background: Atrial fibrillation (AF) affects around 6 million Americans. AF management involves pharmacologic therapy and/or interventional procedures to control rate and rhythm, as well as anticoagulation for stroke prevention. Different populations may respond differently to distinct management strategies.

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Purpose Of Review: This review summarizes contemporary data on unique cardiovascular disease (CVD) risk factors in Hispanic individuals in the USA, and how addressing these factors is important in addressing health equity.

Recent Findings: Recent studies have shown high rates of traditional CVD risk factors in Hispanic individuals such as obesity, hypertension, diabetes, hyperlipidemia, and emerging CVD risk factors like hypertensive disorders of pregnancy, psychological stress, and occupational exposures. However, most studies fail to consider the significant heterogeneity in risk factor burden and outcomes in atherosclerotic CVD by Hispanic subgroup.

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Background: There remains uncertainty regarding optimal primary atherosclerotic cardiovascular disease (ASCVD) prevention practices for older adults.

Objective: To assess statin treatment patterns and incident ASCVD among older patients for primary prevention across the spectrum of ASCVD risk.

Design: Retrospective cohort study of participants without ASCVD aged 65-79 years.

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Background: The value of healthcare chaplains to patient care is increasingly recognized. However, physicians' understandings of the role of pastoral care have been reported to be poor, which have raised concerns about the quality of chaplain-physician interactions and their impact on patient care. These interactions, particularly from the perspective of the chaplain, have not been extensively investigated.

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Purpose Of Review: Racial, ethnic, and gender disparities in cardiovascular care are well-documented. This review aims to highlight the disparities and impact on a group particularly vulnerable to disparities, women from racial/ethnic minority backgrounds.

Recent Findings: Women from racial/ethnic minority backgrounds remain underrepresented in major cardiovascular trials, limiting the generalizability of cardiovascular research to this population.

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Objectives: Examine well-being, measured as burnout and professional fulfillment, across critical care healthcare professionals, ICUs, and hospitals within a health system; examine the impact of the coronavirus disease 2019 pandemic.

Design: To complement a longitudinal survey administered to medical critical care physicians at the end of an ICU rotation, which began in May 2018, we conducted a cross-sectional survey among critical care professionals across four hospitals in December 2018 to January 2019. We report the results of the cross-sectional survey and, to examine the impact of the coronavirus disease 2019 pandemic, the longitudinal survey results from July 2019 to May 2020.

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